| Identification |
|---|
| HMDB Protein ID
| CDBP00758 |
| Secondary Accession Numbers
| Not Available |
| Name
| Glutathione S-transferase kappa 1 |
| Description
| Not Available |
| Synonyms
|
- GST 13-13
- GST class-kappa
- GSTK1-1
- Glutathione S-transferase subunit 13
- hGSTK1
|
| Gene Name
| GSTK1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in protein disulfide oxidoreductase activity |
| Specific Function
| Significant glutathione conjugating activity is found only with the model substrate, 1-chloro-2,4-dinitrobenzene (CDNB).
|
| GO Classification
|
| Biological Process |
| glutathione metabolic process |
| Cellular Component |
| peroxisome |
| mitochondrial inner membrane |
| Component |
| cell part |
| periplasmic space |
| outer membrane-bounded periplasmic space |
| Function |
| catalytic activity |
| oxidoreductase activity, acting on a sulfur group of donors |
| disulfide oxidoreductase activity |
| protein disulfide oxidoreductase activity |
| oxidoreductase activity |
| Molecular Function |
| glutathione peroxidase activity |
| glutathione transferase activity |
| protein disulfide oxidoreductase activity |
|
| Cellular Location
|
- Peroxisome
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Metabolism of xenobiotics by cytochrome P450 | Not Available |  | | Drug metabolism - cytochrome P450 | Not Available |  | | Peroxisome | Not Available |  | | Chemical carcinogenesis | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 7 |
| Locus
| 7q34 |
| SNPs
| GSTK1 |
| Gene Sequence
|
>681 bp
ATGGGGCCCCTGCCGCGCACCGTGGAGCTCTTCTATGACGTGCTGTCCCCCTACTCCTGG
CTGGGCTTCGAGATCCTGTGCCGGTATCAGAATATCTGGAACATCAACCTGCAGTTGCGG
CCCAGCCTCATAACAGGGATCATGAAAGACAGTGGAAACAAGCCTCCAGGTCTGCTTCCC
CGCAAAGGACTATACATGGCAAATGACTTAAAGCTCCTGAGACACCATCTCCAGATTCCC
ATCCACTTCCCCAAGGATTTCTTGTCTGTGATGCTTGAAAAAGGAAGTTTGTCTGCCATG
CGTTTCCTCACCGCCGTGAACTTGGAGCATCCAGAGATGCTGGAGAAAGCGTCCCGGGAG
CTGTGGATGCGCGTCTGGTCAAGGAATGAAGACATCACCGAGCCGCAGAGCATCCTGGCG
GCTGCAGAGAAGGCTGGTATGTCTGCAGAACAAGCCCAGGGACTTCTGGAAAAGATCGCA
ACGCCAAAGGTGAAGAACCAGCTCAAGGAGACCACTGAGGCAGCCTGCAGATACGGAGCC
TTTGGGCTGCCCATCACCGTGGCCCATGTGGATGGCCAAACCCACATGTTATTTGGCTCT
GACCGGATGGAGCTGCTGGCGCACCTGCTGGGAGAGAAGTGGATGGGCCCTATACCTCCA
GCCGTGAATGCCAGACTTTAA
|
| Protein Properties |
|---|
| Number of Residues
| 226 |
| Molecular Weight
| 31565.605 |
| Theoretical pI
| 8.737 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Glutathione S-transferase kappa 1
MGPLPRTVELFYDVLSPYSWLGFEILCRYQNIWNINLQLRPSLITGIMKDSGNKPPGLLP
RKGLYMANDLKLLRHHLQIPIHFPKDFLSVMLEKGSLSAMRFLTAVNLEHPEMLEKASRE
LWMRVWSRNEDITEPQSILAAAEKAGMSAEQAQGLLEKIATPKVKNQLKETTEAACRYGA
FGLPITVAHVDGQTHMLFGSDRMELLAHLLGEKWMGPIPPAVNARL
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| Q9Y2Q3 |
| UniProtKB/Swiss-Prot Entry Name
| GSTK1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AY520571 |
| GeneCard ID
| GSTK1 |
| GenAtlas ID
| GSTK1 |
| HGNC ID
| HGNC:16906 |
| References |
|---|
| General References
| Not Available |