Cannabis Compound Database: Showing Protein Fructose-1,6-bisphosphatase 1 (CDBP00748)

Identification Biological properties Gene properties Protein properties External links References XML Show 4 compounds

Identification

HMDB Protein ID

CDBP00748

Secondary Accession Numbers

Not Available

Name

Fructose-1,6-bisphosphatase 1

Description

Not Available

Synonyms

D-fructose-1,6-bisphosphate 1-phosphohydrolase 1
FBPase 1

Gene Name

FBP1

Protein Type

Enzyme

Biological Properties

General Function

Involved in phosphoric ester hydrolase activity

Specific Function

Not Available

GO Classification

Biological Process
cellular response to insulin stimulus
gluconeogenesis
negative regulation of cell growth
cellular response to magnesium ion
fructose 6-phosphate metabolic process
negative regulation of glycolysis
negative regulation of Ras protein signal transduction
protein homotetramerization
regulation of gluconeogenesis
small molecule metabolic process
fructose metabolic process
cellular response to drug
Cellular Component
cytosol
Function
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
phosphoric ester hydrolase activity
Molecular Function
AMP binding
fructose 1,6-bisphosphate 1-phosphatase activity
metal ion binding
monosaccharide binding
Process
metabolic process
primary metabolic process
carbohydrate metabolic process

Cellular Location

Cytoplasmic

Pathways

Name	SMPDB/Pathwhiz	KEGG
Glycolysis / Gluconeogenesis	Not Available
Fructose and mannose metabolism	Not Available
Insulin signaling pathway	Not Available
Fructose and Mannose Degradation
Fructosuria		Not Available

Gene Properties

Chromosome Location

Locus

9q22.3

SNPs

FBP1

Gene Sequence

>1017 bp
ATGGCTGACCAGGCGCCCTTCGACACGGACGTCAACACCCTGACCCGCTTCGTCATGGAG
GAGGGCAGGAAGGCCCGCGGCACGGGCGAGTTGACCCAGCTGCTCAACTCGCTCTGCACA
GCAGTCAAAGCCATCTCTTCGGCGGTGCGCAAGGCGGGCATCGCGCACCTCTATGGCATT
GCTGGTTCTACCAACGTGACAGGTGATCAAGTTAAGAAGCTGGACGTCCTCTCCAACGAC
CTGGTTATGAACATGTTAAAGTCATCCTTTGCCACGTGTGTTCTCGTGTCAGAAGAAGAT
AAACACGCCATCATAGTGGAACCGGAGAAAAGGGGTAAATATGTGGTCTGTTTTGATCCC
CTTGATGGATCTTCCAACATCGATTGCCTTGTGTCCGTTGGAACCATTTTTGGCATCTAT
AGAAAGAAATCAACTGATGAGCCTTCTGAGAAGGATGCTCTGCAACCAGGCCGGAACCTG
GTGGCAGCCGGCTACGCACTGTATGGCAGTGCCACCATGCTGGTCCTTGCCATGGACTGT
GGGGTCAACTGCTTCATGCTGGACCCGGCCATCGGGGAGTTCATTTTGGTGGACAAGGAT
GTGAAGATAAAAAAGAAAGGTAAAATCTACAGCCTTAACGAGGGCTACGCCAGGGACTTT
GACCCTGCCGTCACTGAGTACATCCAGAGGAAGAAGTTCCCCCCAGATAATTCAGCTCCT
TATGGGGCCCGGTATGTGGGCTCCATGGTGGCTGATGTTCATCGCACTCTGGTCTACGGA
GGGATATTTCTGTACCCCGCTAACAAGAAGAGCCCCAATGGAAAGCTGAGACTGCTGTAC
GAATGCAACCCCATGGCCTACGTCATGGAGAAGGCTGGGGGAATGGCCACCACTGGGAAG
GAGGCCGTGTTAGACGTCATTCCCACAGACATTCACCAGAGGGCGCCGGTGATCTTGGGA
TCCCCCGACGACGTGCTCGAGTTCCTGAAGGTGTATGAGAAGCACTCTGCCCAGTGA

Protein Properties

Number of Residues

338

Molecular Weight

36842.145

Theoretical pI

6.986

Pfam Domain Function

FBPase (PF00316 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Fructose-1,6-bisphosphatase 1
MADQAPFDTDVNTLTRFVMEEGRKARGTGELTQLLNSLCTAVKAISSAVRKAGIAHLYGI
AGSTNVTGDQVKKLDVLSNDLVMNMLKSSFATCVLVSEEDKHAIIVEPEKRGKYVVCFDP
LDGSSNIDCLVSVGTIFGIYRKKSTDEPSEKDALQPGRNLVAAGYALYGSATMLVLAMDC
GVNCFMLDPAIGEFILVDKDVKIKKKGKIYSLNEGYAKDFDPAVTEYIQRKKFPPDNSAP
YGARYVGSMVADVHRTLVYGGIFLYPANKKSPNGKLRLLYECNPMAYVMEKAGGMATTGK
EAVLDVIPTDIHQRAPVILGSPDDVLEFLKVYEKHSAQ

External Links

GenBank ID Protein

16579888

UniProtKB/Swiss-Prot ID

P09467

UniProtKB/Swiss-Prot Entry Name

F16P1_HUMAN

PDB IDs