| Identification |
|---|
| HMDB Protein ID
| CDBP00746 |
| Secondary Accession Numbers
| Not Available |
| Name
| Fructose-1,6-bisphosphatase isozyme 2 |
| Description
| Not Available |
| Synonyms
|
- D-fructose-1,6-bisphosphate 1-phosphohydrolase 2
- FBPase 2
|
| Gene Name
| FBP2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in phosphoric ester hydrolase activity |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| small molecule metabolic process |
| fructose metabolic process |
| gluconeogenesis |
| Cellular Component |
| cytosol |
| Function |
| hydrolase activity, acting on ester bonds |
| catalytic activity |
| hydrolase activity |
| phosphoric ester hydrolase activity |
| Molecular Function |
| metal ion binding |
| fructose 1,6-bisphosphate 1-phosphatase activity |
| fructose-2,6-bisphosphate 2-phosphatase activity |
| Process |
| metabolic process |
| primary metabolic process |
| carbohydrate metabolic process |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Glycolysis / Gluconeogenesis | Not Available |  | | Fructose and mannose metabolism | Not Available |  | | Insulin signaling pathway | Not Available |  |
|
| Gene Properties |
|---|
| Chromosome Location
| 9 |
| Locus
| 9q22.3 |
| SNPs
| FBP2 |
| Gene Sequence
|
>1020 bp
ATGACGGACAGAAGCCCCTTCGAAACCGACATGCTCACCCTGACCCGCTACGTTATGGAA
AAGGGGCGTCAGGCCAAAGGGACTGGGGAGCTCACCCAGCTGCTGAACTCAATGCTGACG
GCCATCAAAGCCATCTCCTCGGCTGTGCGCAAGGCCGGTCTGGCCCACCTGTATGGAATC
GCAGGAAGCGTTAACGTGACGGGAGATGAGGTGAAGAAACTGGATGTGCTATCCAATTCC
CTGGTGATCAACATGGTCCAATCCTCCTATAGTACCTGCGTCCTGGTCTCAGAAGAGAAT
AAGGACGCCATCATCACCGCCAAGGAGAAGCGGGGGAAATACGTGGTCTGCTTTGACCCA
CTGGATGGATCTTCCAATATTGACTGCCTGGCCTCCATCGGAACCATCTTTGCCATCTAT
AGAAAGACCTCAGAGGATGAGCCTTCTGAAAAGGATGCCCTGCAGTGTGGCCGCAATATT
GTGGCCGCAGGTTATGCGCTGTACGGTAGTGCAACCCTGGTGGCTCTCTCCACAGGGCAA
GGCGTGGACCTCTTCATGCTTGACCCGGCTCTTGGTGAATTTGTCCTGGTGGAAAAAGAT
GTCAAGATTAAGAAGAAAGGAAAGATTTACAGCCTGAATGAGGGCTATGCCAAGTATTTT
GATGCGGCCACCACTGAATATGTGCAGAAAAAGAAATTCCCTGAGGATGGCAGTGCTCCC
TATGGGGCCAGGTATGTGGGCTCCATGGTGGCTGACGTGCACCGCACCCTGGTCTATGGA
GGAATCTTCCTGTACCCAGCCAACCAGAAGAGCCCTAAGGGCAAGCTCCGGCTCCTGTAT
GAATGCAATCCCGTGGCCTACATCATTGAGCAGGCAGGAGGCTTGGCGACCACGGGGACC
CAGCCTGTACTGGACGTGAAGCCCGAGGCAATTCACCAGCGAGTCCCCCTCATTCTGGGG
TCACCAGAGGATGTGCAGGAATATCTCACCTGTGTGCAGAAAAATCAGGCAGGCAGCTAG
|
| Protein Properties |
|---|
| Number of Residues
| 339 |
| Molecular Weight
| 36742.84 |
| Theoretical pI
| 7.23 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Fructose-1,6-bisphosphatase isozyme 2
MTDRSPFETDMLTLTRYVMEKGRQAKGTGELTQLLNSMLTAIKAISSAVRKAGLAHLYGI
AGSVNVTGDEVKKLDVLSNSLVINMVQSSYSTCVLVSEENKDAIITAKEKRGKYVVCFDP
LDGSSNIDCLASIGTIFAIYRKTSEDEPSEKDALQCGRNIVAAGYALYGSATLVALSTGQ
GVDLFMLDPALGEFVLVEKDVKIKKKGKIYSLNEGYAKYFDAATTEYVQKKKFPEDGSAP
YGARYVGSMVADVHRTLVYGGIFLYPANQKSPKGKLRLLYECNPVAYIIEQAGGLATTGT
QPVLDVKPEAIHQRVPLILGSPEDVQEYLTCVQKNQAGS
|
| External Links |
|---|
| GenBank ID Protein
| 55662226 |
| UniProtKB/Swiss-Prot ID
| O00757 |
| UniProtKB/Swiss-Prot Entry Name
| F16P2_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AL161728 |
| GeneCard ID
| FBP2 |
| GenAtlas ID
| FBP2 |
| HGNC ID
| HGNC:3607 |
| References |
|---|
| General References
| Not Available |