| Identification |
|---|
| HMDB Protein ID
| CDBP00726 |
| Secondary Accession Numbers
| Not Available |
| Name
| 3-mercaptopyruvate sulfurtransferase |
| Description
| Not Available |
| Synonyms
|
- MST
|
| Gene Name
| MPST |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in thiosulfate sulfurtransferase activity |
| Specific Function
| Transfer of a sulfur ion to cyanide or to other thiol compounds. Also has weak rhodanese activity. May have a role in cyanide degradation or in thiosulfate biosynthesis.
|
| GO Classification
|
| Biological Process |
| response to toxin |
| cyanate catabolic process |
| Cellular Component |
| mitochondrion |
| mitochondrial inner membrane |
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring sulfur-containing groups |
| sulfurtransferase activity |
| thiosulfate sulfurtransferase activity |
| Molecular Function |
| thiosulfate sulfurtransferase activity |
| 3-mercaptopyruvate sulfurtransferase activity |
| Process |
| transport |
| anion transport |
| inorganic anion transport |
| sulfate transport |
| ion transport |
| establishment of localization |
|
| Cellular Location
|
- Cytoplasm
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Cysteine and methionine metabolism | Not Available |  | | Sulfur relay system | Not Available |  | | Cysteine Metabolism |    | | | Beta-mercaptolactate-cysteine disulfiduria |    | Not Available | | Cystinosis, ocular nonnephropathic |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 22 |
| Locus
| 22q13.1 |
| SNPs
| MPST |
| Gene Sequence
|
>894 bp
ATGGCTTCGCCGCAGCTCTGCCGCGCGCTGGTGTCGGCGCAATGGGTGGCGGAGGCGCTG
CGGGCCCCGCGCGCTGGGCAGCCTCTGCAGCTGCTGGACGCCTCCTGGTACCTGCCGAAG
CTGGGGCGCGACGCGCGACGCGAGTTCGAGGAGCGCCACATCCCGGGCGCCGCTTTCTTC
GACATCGACCAGTGCAGCGACCGCACCTCGCCCTACGACCACATGCTGCCCGGGGCCGAG
CATTTCGCGGAGTACGCAGGCCGCCTGGGCGTGGGCGCGGCCACCCACGTCGTGATCTAC
GACGCCAGCGACCAGGGCCTCTACTCCGCCCCGCGCGTCTGGTGGATGTTCCGCGCCTTC
GGCCACCACGCCGTGTCACTGCTTGATGGCGGCCTCCGCCACTGGCTGCGCCAGAACCTC
CCGCTCAGCTCCGGCAAGAGCCAACCTGCTCCCGCCGAGTTCCGCGCTCAGCTCGACCCC
GCCTTCATCAAGACCTACGAGGACATCAAGGAGAACCTGGAATCCCGGCGCTTCCAGGTG
GTGGACTCCCGAGCCACTGGCAGGTTCCGCGGCACCGAGCCCGAGCCCCGAGACGGCATT
GAACCTGGCCACATCCCAGGTACCGTGAACATCCCCTTCACAGACTTCCTGAGCCAGGAG
GGGCTGGAGAAGAGCCCTGAGGAGATCCGCCATCTGTTCCAGGAGAAGAAAGTGGACCTG
TCTAAGCCACTGGTGGCCACGTGTGGCTCTGGCGTCACAGCCTGCCACGTGGCACTAGGG
GCCTACCTCTGCGGCAAGCCAGACGTGCCCATCTACGATGGCTCCTGGGTGGAGTGGTAC
ATGCGCGCCCGGCCCGAGGATGTCATCTCAGAGGGCCGGGGGAAGACCCACTGA
|
| Protein Properties |
|---|
| Number of Residues
| 297 |
| Molecular Weight
| 33178.15 |
| Theoretical pI
| 6.601 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>3-mercaptopyruvate sulfurtransferase
MASPQLCRALVSAQWVAEALRAPRAGQPLQLLDASWYLPKLGRDARREFEERHIPGAAFF
DIDQCSDRTSPYDHMLPGAEHFAEYAGRLGVGAATHVVIYDASDQGLYSAPRVWWMFRAF
GHHAVSLLDGGLRHWLRQNLPLSSGKSQPAPAEFRAQLDPAFIKTYEDIKENLESRRFQV
VDSRATGRFRGTEPEPRDGIEPGHIPGTVNIPFTDFLSQEGLEKSPEEIRHLFQEKKVDL
SKPLVATCGSGVTACHVALGAYLCGKPDVPIYDGSWVEWYMRARPEDVISEGRGKTH
|
| External Links |
|---|
| GenBank ID Protein
| 13097573 |
| UniProtKB/Swiss-Prot ID
| P25325 |
| UniProtKB/Swiss-Prot Entry Name
| THTM_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| BC003508 |
| GeneCard ID
| MPST |
| GenAtlas ID
| MPST |
| HGNC ID
| HGNC:7223 |
| References |
|---|
| General References
| Not Available |