| Identification |
|---|
| HMDB Protein ID
| CDBP00704 |
| Secondary Accession Numbers
| Not Available |
| Name
| Choline-phosphate cytidylyltransferase A |
| Description
| Not Available |
| Synonyms
|
- CCT A
- CCT-alpha
- CT A
- CTP:phosphocholine cytidylyltransferase A
- Phosphorylcholine transferase A
|
| Gene Name
| PCYT1A |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Controls phosphatidylcholine synthesis.
|
| GO Classification
|
| Biological Process |
| response to abiotic stimulus |
| Cellular Component |
| endoplasmic reticulum membrane |
| cytosol |
| glycogen granule |
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| nucleotidyltransferase activity |
| Molecular Function |
| lipid binding |
| choline-phosphate cytidylyltransferase activity |
| Process |
| biosynthetic process |
| metabolic process |
|
| Cellular Location
|
- Cytoplasm
- Peripheral membrane protein
- Membrane
- cytosol
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Glycerophospholipid metabolism | Not Available |  | | Phospholipid Biosynthesis |    | | | Lamivudine Metabolism Pathway |    | Not Available | | Phosphatidylcholine Biosynthesis |    | Not Available | | Phosphatidylcholine Biosynthesis PC(14:0/14:0) |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 3 |
| Locus
| 3q29 |
| SNPs
| PCYT1A |
| Gene Sequence
|
>1104 bp
ATGGATGCACAGTGTTCAGCCAAGGTCAATGCAAGGAAGAGGAGAAAAGAGGCGCCCGGA
CCCAACGGGGCAACAGAAGAAGATGGGGTTCCTTCCAAAGTGCAGCGCTGTGCAGTGGGC
TTACGGCAACCAGCTCCTTTTTCTGATGAAATTGAAGTTGACTTTAGTAAGCCCTATGTC
AGGGTAACTATGGAAGAAGCCAGCAGAGGAACTCCTTGTGAGCGACCTGTGAGAGTTTAT
GCCGATGGAATATTTGACTTATTTCACTCTGGTCACGCCCGAGCTCTGATGCAAGCGAAG
AACCTTTTCCCTAATACGTACCTCATTGTGGGAGTTTGCAGTGATGAGCTCACACACAAC
TTCAAAGGCTTCACGGTGATGAACGAGAATGAGCGCTATGACGCAGTCCAGCACTGCCGC
TACGTGGATGAGGTGGTGAGGAATGCGCCCTGGACGCTGACACCCGAGTTCCTGGCCGAA
CACCGGATTGATTTTGTAGCCCATGATGATATTCCTTATTCATCTGCTGGCAGTGATGAT
GTTTATAAGCACATCAAGGAGGCAGGCATGTTTGCTCCAACACAGAGGACAGAAGGTATC
TCCACATCAGACATCATCACCCGAATTGTGCGGGATTATGATGTGTATGCGAGGCGGAAC
CTGCAGAGGGGCTACACAGCAAAGGAGCTCAATGTCAGCTTTATCAACGAGAAGAAATAC
CACTTGCAGGAGAGGGTTGACAAAGTAAAGAAGAAAGTGAAAGATGTGGAGGAAAAGTCA
AAAGAATTTGTTCAGAAGGTGGAGGAAAAAAGCATTGACCTCATTCAGAAGTGGGAGGAG
AAGTCCCGAGAATTCATTGGAAGTTTTCTGGAAATGTTTGGTCCGGAAGGAGCACTGAAA
CATATGCTGAAAGAGGGGAAGGGCCGGATGCTGCAGGCCATCAGCCCGAAGCAGAGCCCC
AGCAGCAGCCCTACTCGCGAGCGCTCCCCCTCCCCCTCTTTCCGATGGCCCTTCTCCGGC
AAGACTTCCCCACCTTGCTCCCCAGCAAATCTCTCCAGGCACAAGGCTGCAGCCTATGAT
ATCAGTGAGGATGAAGAAGACTAA
|
| Protein Properties |
|---|
| Number of Residues
| 367 |
| Molecular Weight
| 41730.67 |
| Theoretical pI
| 7.261 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Choline-phosphate cytidylyltransferase A
MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV
RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN
FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD
VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY
HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK
HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD
ISEDEED
|
| External Links |
|---|
| GenBank ID Protein
| 28204946 |
| UniProtKB/Swiss-Prot ID
| P49585 |
| UniProtKB/Swiss-Prot Entry Name
| PCY1A_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| BC046355 |
| GeneCard ID
| PCYT1A |
| GenAtlas ID
| PCYT1A |
| HGNC ID
| HGNC:8754 |
| References |
|---|
| General References
| Not Available |