| Identification |
|---|
| HMDB Protein ID
| CDBP00697 |
| Secondary Accession Numbers
| Not Available |
| Name
| Ethanolamine-phosphate cytidylyltransferase |
| Description
| Not Available |
| Synonyms
|
- CTP:phosphoethanolamine cytidylyltransferase
- Phosphorylethanolamine transferase
|
| Gene Name
| PCYT2 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Plays an important role in the biosynthesis of the phospholipid phosphatidylethanolamine. Catalyzes the formation of CDP-ethanolamine.
|
| GO Classification
|
| Biological Process |
| small molecule metabolic process |
| phosphatidylethanolamine biosynthetic process |
| biosynthetic process |
| Cellular Component |
| endoplasmic reticulum membrane |
| Function |
| catalytic activity |
| transferase activity |
| transferase activity, transferring phosphorus-containing groups |
| nucleotidyltransferase activity |
| Molecular Function |
| nucleotidyltransferase activity |
| ethanolamine-phosphate cytidylyltransferase activity |
| Process |
| metabolic process |
| biosynthetic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Glycerophospholipid metabolism | Not Available |  | | Lamivudine Metabolism Pathway |    | Not Available | | Phosphatidylcholine Biosynthesis |    | Not Available | | Phosphatidylcholine Biosynthesis PC(14:0/14:0) |    | Not Available | | Phosphatidylcholine Biosynthesis PC(14:0/14:1(9Z)) |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 17 |
| Locus
| 17q25.3 |
| SNPs
| PCYT2 |
| Gene Sequence
|
>1170 bp
ATGATCCGGAACGGGCGCGGGGCTGCAGGCGGCGCAGAGCAGCCGGGCCCGGGGGGCAGG
CGCGCCGTGAGGGTGTGGTGCGATGGCTGCTATGACATGGTGCATTACGGCCACTCCAAC
CAGCTGCGCCAGGCACGGGCCATGGGTGACTACCTCATCGTAGGCGTGCACACCGATGAG
GAGATCGCCAAGCACAAGGGGCCCCCGGTGTTCACTCAGGAGGAGAGATACAAGATGGTG
CAGGCCATCAAATGGGTGGACGAGGTGGTGCCAGCGGCTCCCTACGTCACTACACTAGAG
ACCCTGGACAAATACAACTGTGACTTCTGTGTTCACGGCAATGACATCACCCTGACTGTA
GATGGCCGGGACACCTATGAGGAAGTAAAGCAGGCTGGGAGGTACAGAGAATGCAAGCGC
ACGCAAGGGGTGTCCACCACAGACCTCGTGGGCCGCATGCTGCTGGTAACCAAAGCCCAT
CACAGCAGCCAGGAGATGTCCTCTGAGTACCGGGAGTATGCAGACAGTTTTGGCAAGTGC
CCTGGTGGGCGGAACCCCTGGACCGGGGTATCCCAGTTCCTGCAGACATCTCAGAAGATC
ATCCAGTTTGCTTCTGGGAAGGAGCCCCAGCCAGGGGAGACAGTCATCTATGTGGCTGGT
GCCTTCGACCTGTTCCACATCGGGCATGTGGACTTCCTGGAGAAGGTGCACAGGCTGGCA
GAGAGGCCCTACATCATCGCGGGCTTACACTTTGACCAGGAGGTCAATCACTACAAGGGG
AAGAACTACCCCATCATGAATCTGCATGAACGGACTCTGAGCGTGCTGGCCTGCCGGTAC
GTGTCAGAAGTGGTGATTGGAGCCCCGTACGCGGTCACAGCAGAGCTCCTAAGTCACTTC
AAGGTGGACCTGGTGTGTCACGGCAAGACAGAAATTATCCCTGACAGGGATGGCTCCGAC
CCATACCAGGAGCCCAAGAGAAGGGGCATCTTCCGTCAGATTGACAGTGGCAGCAACCTC
ACCACAGACCTCATCGTCCAGCGGATCATCACCAACAGGTTGGAGTATGAGGCGCGAAAC
CAGAAGAAGGAAGCCAAGGAGCTGGCCTTCCTGGAGGCTGCCAGGCAGCAGGCGGCACAG
CCCCTGGGGGAGCGCGATGGTGACTTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 389 |
| Molecular Weight
| 35199.52 |
| Theoretical pI
| 6.465 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Ethanolamine-phosphate cytidylyltransferase
MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQARAMGDYLIVGVHTDE
EIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLDKYNCDFCVHGNDITLTV
DGRDTYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHSSQEMSSEYREYADSFGKC
PGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHVDFLEKVHRLA
ERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPYAVTAELLSHF
KVDLVCHGKTEIIPDRDGSDPYQEPKRRGIFRQIDSGSNLTTDLIVQRIITNRLEYEARN
QKKEAKELAFLEAARQQAAQPLGERDGDF
|
| External Links |
|---|
| GenBank ID Protein
| 12653167 |
| UniProtKB/Swiss-Prot ID
| Q99447 |
| UniProtKB/Swiss-Prot Entry Name
| PCY2_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| BC000351 |
| GeneCard ID
| PCYT2 |
| GenAtlas ID
| PCYT2 |
| HGNC ID
| HGNC:8756 |
| References |
|---|
| General References
| Not Available |