Showing Protein Protein-glutamine gamma-glutamyltransferase Z (CDBP00657)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 2 compounds
Identification
HMDB Protein ID CDBP00657
Secondary Accession Numbers Not Available
Name Protein-glutamine gamma-glutamyltransferase Z
Description Not Available
Synonyms
  1. TG(Z)
  2. TGZ
  3. TGase Z
  4. TGase-7
  5. Transglutaminase Z
  6. Transglutaminase-7
Gene Name TGM7
Protein Type Enzyme
Biological Properties
General Function Involved in protein-glutamine gamma-glutamyltransferase activity
Specific Function Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins.
GO Classification
Biological Process
peptide cross-linking
Function
transferase activity, transferring acyl groups
transferase activity, transferring amino-acyl groups
protein-glutamine gamma-glutamyltransferase activity
catalytic activity
transferase activity
Molecular Function
metal ion binding
protein-glutamine gamma-glutamyltransferase activity
Process
metabolic process
macromolecule metabolic process
post-translational protein modification
peptide cross-linking
macromolecule modification
protein modification process
Cellular Location Not Available
Pathways
Gene Properties
Chromosome Location 15
Locus 15q15.2
SNPs TGM7
Gene Sequence 
>2133 bp
ATGGATCAGGTGGCAACCTTGCGGCTTGAGTCTGTCGACCTGCAGAGCTCCAGGAACAAC
AAGGAGCACCACACGCAGGAGATGGGCGTCAAGCGGCTCACTGTGCGCCGCGGCCAGCCC
TTCTACCTCCGGCTGAGCTTCAGCCGACCCTTCCAGTCCCAGAACGACCACATCACCTTT
GTGGCTGAGACCGGACCCAAGCCGTCAGAGCTGCTGGGGACCCGAGCCACATTCTTCCTC
ACCCGGGTCCAGCCCGGGAATGTCTGGAGCGCTTCTGATTTCACCATTGACTCCAACTCT
CTCCAAGTTTCCCTTTTCACACCAGCCAATGCAGTTATTGGCCATTACACTCTGAAAATA
GAGATCTCTCAGGGCCAAGGTCACAGTGTGACTTACCCGCTGGGAACTTTCATCCTACTT
TTTAACCCTTGGAGTCCAGAGGACGACGTCTACCTGCCAAGTGAAATACTGCTGCAGGAG
TATATCATGCGAGATTATGGCTTTGTTTACAAGGGTCATGAAAGATTCATCACCTCCTGG
CCCTGGAACTACGGGCAGTTTGAAGAGGACATCATAGACATCTGCTTTGAGATCCTGAAC
AAGAGCCTGTATCACTTAAAGAACCCGGCCAAAGACTGTTCCCAGCGGAACGACGTGGTG
TATGTGTGCAGGGTGGTGAGTGCCATGATCAACAGCAACGATGACAATGGCGTGCTGCAG
GGGAACTGGGGCGAGGACTACTCCAAAGGGGTCAGTCCTCTGGAGTGGAAGGGCAGTGTG
GCCATCCTACAGCAGTGGTCAGCCAGGGGCGGGCAGCCTGTGAAGTACGGACAGTGCTGG
GTCTTCGCCTCTGTTATGTGCACCGTAATGAGATGCTTAGGTGTTCCAACCCGTGTTGTT
TCCAATTTCCGTTCCGCGCACAACGTGGATAGGAACTTGACCATCGATACGTACTATGAC
CGAAATGCCGAGATGCTGTCAACTCAGAAACGAGACAAAATATGGAACTTCCACGTCTGG
AATGAGTGCTGGATGATCCGGAAAGATCTCCCACCAGGATACAACGGGTGGCAGGTTCTG
GACCCCACTCCCCAGCAGACCAGCAGTGGGCTGTTCTGCTGTGGCCCTGCCTCTGTGAAG
GCCATCAGGGAAGGGGATGTCCACCTGGCCTATGACACCCCTTTTGTGTATGCCGAGGTG
AACGCCGATGAAGTCATTTGGCTCCTTGGGGATGGCCAGGCCCAGGAAATCCTGGCCCAC
AACACCAGTTCCATCGGGAAGGAGATCAGCACTAAGATGGTGGGGTCAGACCAGCGCCAG
AGCATCACCAGCTCCTACAAGTACCCAGAAGGATCCCCTGAGGAGAGAGCTGTCTTCATG
AAGGCTTCTCGGAAAATGCTGGGCCCCCAAAGAGCTTCTTTGCCCTTCCTGGATCTCCTG
GAGTCTGGGGGTCTTAGGGATCAGCCAGCGCAGCTGCAGCTTCACCTGGCCAGGATACCC
GAGTGGGGCCAGGACCTGCAGCTGCTGCTGCGTATCCAGAGGGTGCCAGACAGCACCCAC
CCTCGGGGGCCCATCGGACTGGTGGTGCGCTTCTGTGCACAGGCCCTGCTGCATGGGGGT
GGTACCCAGAAGCCCTTCTGGAGGCACACAGTGCGGATGAACCTGGACTTTGGGAAGGAG
ACACAGTGGCCGCTCCTCCTGCCCTACAGCAATTACAGAAACAAGCTAACGGACGAAAAG
CTCATCCGCGTGTCTGGCATCGCGGAGGTTGAAGAGACAGGGAGGTCCATGCTGGTCCTA
AAAGATATCTGTCTGGAGCCTCCCCACTTGTCTATTGAGGTGTCTGAGAGGGCTGAGGTG
GGCAAGGCGCTGAGAGTCCATGTCACCCTCACCAACACCTTAATGGTGGCTCTGAGCAGC
TGCACGATGGTGCTGGAAGGAAGCGGCCTCATCAATGGGCAGATAGCAAAGGACCTTGGG
ACTCTGGTGGCCGGACACACCCTCCAAATTCAACTGGACCTCTACCCGACCAAAGCTGGA
CCCCGCCAGCTCCAGGTTCTCATCAGCAGCAACGAGGTCAAGGAGATCAAAGGCTACAAG
GACATATTCGTCACTGTGGCTGGGGCTCCCTGA
Protein Properties
Number of Residues 710
Molecular Weight 79940.615
Theoretical pI 7.0
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Protein-glutamine gamma-glutamyltransferase Z
MDQVATLRLESVDLQSSRNNKEHHTQEMGVKRLTVRRGQPFYLRLSFSRPFQSQNDHITF
VAETGPKPSELLGTRATFFLTRVQPGNVWSASDFTIDSNSLQVSLFTPANAVIGHYTLKI
EISQGQGHSVTYPLGTFILLFNPWSPEDDVYLPSEILLQEYIMRDYGFVYKGHERFITSW
PWNYGQFEEDIIDICFEILNKSLYHLKNPAKDCSQRNDVVYVCRVVSAMINSNDDNGVLQ
GNWGEDYSKGVSPLEWKGSVAILQQWSARGGQPVKYGQCWVFASVMCTVMRCLGVPTRVV
SNFRSAHNVDRNLTIDTYYDRNAEMLSTQKRDKIWNFHVWNECWMIRKDLPPGYNGWQVL
DPTPQQTSSGLFCCGPASVKAIREGDVHLAYDTPFVYAEVNADEVIWLLGDGQAQEILAH
NTSSIGKEISTKMVGSDQRQSITSSYKYPEGSPEERAVFMKASRKMLGPQRASLPFLDLL
ESGGLRDQPAQLQLHLARIPEWGQDLQLLLRIQRVPDSTHPRGPIGLVVRFCAQALLHGG
GTQKPFWRHTVRMNLDFGKETQWPLLLPYSNYRNKLTDEKLIRVSGIAEVEETGRSMLVL
KDICLEPPHLSIEVSERAEVGKALRVHVTLTNTLMVALSSCTMVLEGSGLINGQIAKDLG
TLVAGHTLQIQLDLYPTKAGPRQLQVLISSNEVKEIKGYKDIFVTVAGAP
GenBank ID Protein 15425755
UniProtKB/Swiss-Prot ID Q96PF1
UniProtKB/Swiss-Prot Entry Name TGM7_HUMAN
PDB IDs Not Available
GenBank Gene ID AF363393
GeneCard ID TGM7
GenAtlas ID TGM7
HGNC ID HGNC:30790
References
General References Not Available