Cannabis Compound Database: Showing Protein Pyridoxine-5'-phosphate oxidase (CDBP00638)

Identification Biological properties Gene properties Protein properties External links References XML Show 10 compounds

Identification

HMDB Protein ID

CDBP00638

Secondary Accession Numbers

Not Available

Name

Pyridoxine-5'-phosphate oxidase

Description

Not Available

Synonyms

Pyridoxamine-phosphate oxidase

Gene Name

PNPO

Protein Type

Enzyme

Biological Properties

General Function

Involved in pyridoxamine-phosphate oxidase activity

Specific Function

Catalyzes the oxidation of either pyridoxine 5'-phosphate (PNP) or pyridoxamine 5'-phosphate (PMP) into pyridoxal 5'-phosphate (PLP).

GO Classification

Biological Process
pyridoxine biosynthetic process
vitamin B6 metabolic process
Cellular Component
cytosol
Function
oxidoreductase activity, acting on the ch-nh2 group of donors, oxygen as acceptor
pyridoxamine-phosphate oxidase activity
fmn binding
oxidoreductase activity
binding
nucleotide binding
catalytic activity
oxidoreductase activity, acting on the ch-nh2 group of donors
Molecular Function
FMN binding
pyridoxamine-phosphate oxidase activity
Process
metabolic process
small molecule metabolic process
vitamin metabolic process
water-soluble vitamin metabolic process
vitamin b6 metabolic process
pyridoxine metabolic process
pyridoxine biosynthetic process
oxidation reduction

Cellular Location

Not Available

Pathways

Name	SMPDB/Pathwhiz	KEGG
B6 vitamer interconversion	Not Available	Not Available
Vitamin B6 Metabolism
Hypophosphatasia		Not Available

Gene Properties

Chromosome Location

Locus

17q21.32

SNPs

PNPO

Gene Sequence

>786 bp
ATGACGTGCTGGCTGCGGGGCGTCACGGCGACGTTCGGGCGACCTGCCGAGTGGCCAGGC
TACCTCAGTCACCTGTGTGGTCGCAGTGCTGCCATGGACCTGGGACCCATGCGCAAGAGT
TACCGCGGGGACCGAGAGGCATTTGAGGAGACTCATCTGACCTCCCTTGACCCAGTGAAA
CAGTTTGCTGCCTGGTTTGAGGAGGCTGTTCAGTGTCCTGACATAGGGGAAGCCAATGCC
ATGTGTCTGGCTACCTGCACCAGAGATGGAAAACCCTCTGCTCGCATGTTGCTGCTGAAG
GGCTTCGGGAAAGATGGCTTCCGCTTCTTCACTAACTTCGAGAGTCGAAAAGGAAAAGAG
CTGGACTCTAATCCCTTTGCTTCCCTTGTCTTCTACTGGGAGCCACTTAACCGTCAGGTG
CGTGTGGAAGGCCCTGTGAAGAAACTGCCTGAGGAGGAGGCTGAGTGCTACTTCCACTCC
CGCCCCAAGAGCAGCCAGATTGGGGCTGTGGTCAGCCACCAGAGTTCTGTGATCCCTGAT
CGGGAGTATCTGAGAAAGAAAAATGAGGAACTGGAACAGCTCTACCAGGATCAAGAGGTG
CCCAAGCCAAAATCCTGGGGTGGCTATGTCCTGTACCCTCAGGTGATGGAGTTCTGGCAA
GGTCAAACCAACCGCCTGCATGACCGGATAGTCTTTCGGCGGGGCCTACCCACAGGAGAT
TCCCCTTTGGGGCCCATGACCCACCGCGGGGAGGAAGACTGGCTCTATGAGAGACTTGCA
CCTTAA

Protein Properties

Number of Residues

261

Molecular Weight

29987.79

Theoretical pI

7.071

Pfam Domain Function

PNPOx_C (PF10590 )
Pyridox_oxidase (PF01243 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Pyridoxine-5'-phosphate oxidase
MTCWLRGVTATFGRPAEWPGYLSHLCGRSAAMDLGPMRKSYRGDREAFEETHLTSLDPVK
QFAAWFEEAVQCPDIGEANAMCLATCTRDGKPSARMLLLKGFGKDGFRFFTNFESRKGKE
LDSNPFASLVFYWEPLNRQVRVEGPVKKLPEEEAECYFHSRPKSSQIGAVVSHQSSVIPD
REYLRKKNEELEQLYQDQEVPKPKSWGGYVLYPQVMEFWQGQTNRLHDRIVFRRGLPTGD
SPLGPMTHRGEEDWLYERLAP

External Links

GenBank ID Protein

Not Available

UniProtKB/Swiss-Prot ID

Q9NVS9

UniProtKB/Swiss-Prot Entry Name

PNPO_HUMAN

PDB IDs