| Identification |
|---|
| HMDB Protein ID
| CDBP00605 |
| Secondary Accession Numbers
| Not Available |
| Name
| ADP-ribose pyrophosphatase, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- ADP-ribose diphosphatase
- ADP-ribose phosphohydrolase
- ADPR-PPase
- Adenosine diphosphoribose pyrophosphatase
- Nucleoside diphosphate-linked moiety X motif 9
- Nudix motif 9
|
| Gene Name
| NUDT9 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in hydrolase activity |
| Specific Function
| Hydrolyzes ADP-ribose (ADPR) to AMP and ribose 5'-phosphate.
|
| GO Classification
|
| Biological Process |
| IDP catabolic process |
| ADP catabolic process |
| Cellular Component |
| intracellular |
| mitochondrion |
| Function |
| catalytic activity |
| hydrolase activity |
| Molecular Function |
| ADP-sugar diphosphatase activity |
| adenosine-diphosphatase activity |
| ADP-ribose diphosphatase activity |
|
| Cellular Location
|
- Isoform 1:Mitochondrion
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 4 |
| Locus
| 4q22.1 |
| SNPs
| NUDT9 |
| Gene Sequence
|
>1053 bp
ATGGCGGGACGCCTCCTGGGAAAGGCTTTAGCCGCGGTGTCTCTCTCTCTGGCCTTGGCC
TCTGTGACTATCAGGTCCTCGCGCTGCCGCGGCATCCAGGCGTTCAGAAACTCGTTTTCA
TCTTCTTGGTTTCATCTTAATACCAACGTCATGTCTGGTTCTAATGGTTCCAAAGAAAAT
TCTCACAATAAGGCTCGGACGTCTCCTTACCCAGGTTCAAAAGTTGAACGAAGCCAGGTT
CCTAATGAGAAAGTGGGCTGGCTTGTTGAGTGGCAAGACTATAAGCCTGTGGAATACACT
GCAGTCTCTGTCTTGGCTGGACCCAGGTGGGCAGATCCTCAGATCAGTGAAAGTAATTTT
TCTCCCAAGTTTAACGAAAAGGATGGGCATGTTGAGAGAAAGAGCAAGAATGGCCTGTAT
GAGATTGAAAATGGAAGACCGAGAAATCCTGCAGGACGGACTGGACTGGTGGGCCGGGGG
CTTTTGGGGCGATGGGGCCCAAATCACGCTGCAGATCCCATTATAACCAGATGGAAAAGG
GATAGCAGTGGAAATAAAATCATGCATCCTGTTTCTGGGAAGCATATCTTACAATTTGTT
GCAATAAAAAGGAAAGACTGTGGAGAATGGGCAATCCCAGGGGGGATGGTGGATCCAGGA
GAGAAGATTAGTGCCACACTGAAAAGAGAATTTGGTGAGGAAGCTCTCAACTCCTTACAG
AAAACCAGTGCTGAGAAGAGAGAAATAGAGGAAAAGTTGCACAAACTCTTCAGCCAAGAC
CACCTAGTGATATATAAGGGATATGTTGATGATCCTCGAAACACTGATAATGCATGGATG
GAGACAGAAGCTGTGAACTACCATGACGAAACAGGTGAGATAATGGATAATCTTATGCTA
GAAGCTGGAGATGATGCTGGAAAAGTGAAATGGGTGGACATCAATGATAAACTGAAGCTT
TATGCCAGTCACTCTCAATTCATCAAACTTGTGGCTGAGAAACGAGATGCACACTGGAGC
GAGGACTCTGAAGCTGACTGCCATGCGTTGTAG
|
| Protein Properties |
|---|
| Number of Residues
| 350 |
| Molecular Weight
| 35448.725 |
| Theoretical pI
| 8.232 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>ADP-ribose pyrophosphatase, mitochondrial
MAGRLLGKALAAVSLSLALASVTIRSSRCRGIQAFRNSFSSSWFHLNTNVMSGSNGSKEN
SHNKARTSPYPGSKVERSQVPNEKVGWLVEWQDYKPVEYTAVSVLAGPRWADPQISESNF
SPKFNEKDGHVERKSKNGLYEIENGRPRNPAGRTGLVGRGLLGRWGPNHAADPIITRWKR
DSSGNKIMHPVSGKHILQFVAIKRKDCGEWAIPGGMVDPGEKISATLKREFGEEALNSLQ
KTSAEKREIEEKLHKLFSQDHLVIYKGYVDDPRNTDNAWMETEAVNYHDETGEIMDNLML
EAGDDAGKVKWVDINDKLKLYASHSQFIKLVAEKRDAHWSEDSEADCHAL
|
| External Links |
|---|
| GenBank ID Protein
| 14160858 |
| UniProtKB/Swiss-Prot ID
| Q9BW91 |
| UniProtKB/Swiss-Prot Entry Name
| NUDT9_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AY026252 |
| GeneCard ID
| NUDT9 |
| GenAtlas ID
| NUDT9 |
| HGNC ID
| HGNC:8056 |
| References |
|---|
| General References
| Not Available |