Showing Protein Adenylate kinase isoenzyme 4, mitochondrial (CDBP00555)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 4 compounds
Identification
HMDB Protein ID CDBP00555
Secondary Accession Numbers Not Available
Name Adenylate kinase isoenzyme 4, mitochondrial
Description Not Available
Synonyms
  1. ATP-AMP transphosphorylase
  2. Adenylate kinase 3-like
Gene Name AK4
Protein Type Enzyme
Biological Properties
General Function Involved in ATP binding
Specific Function Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. May also be active with GTP (By similarity).
GO Classification
Biological Process
response to organic nitrogen
ATP metabolic process
AMP metabolic process
GTP metabolic process
response to organic cyclic compound
Cellular Component
mitochondrial matrix
Function
phosphotransferase activity, phosphate group as acceptor
transferase activity
adenylate kinase activity
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleobase, nucleoside, nucleotide kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
binding
catalytic activity
nucleotide kinase activity
Molecular Function
ATP binding
GTP binding
adenylate kinase activity
nucleoside triphosphate adenylate kinase activity
Process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
metabolic process
Cellular Location
  1. Mitochondrion matrix
Pathways
Gene Properties
Chromosome Location 1
Locus 1p31.3
SNPs AK4
Gene Sequence 
>672 bp
ATGGCTTCCAAACTCCTGCGCGCGGTCATCCTCGGGCCGCCCGGCTCGGGCAAGGGCACC
GTGTGCCAGAGGATCGCCCAGAACTTTGGTCTCCAGCATCTCTCCAGCGGCCACTTCTTG
CGGGAGAACATCAAGGCCAGCACCGAAGTTGGTGAGATGGCAAAGCAGTATATAGAGAAA
AGTCTTTTGGTTCCAGACCATGTGATCACACGCCTAATGATGTCCGAGTTGGAGAACAGG
CGTGGCCAGCACTGGCTCCTTGATGGTTTTCCTAGGACATTAGGACAAGCCGAAGCCCTG
GACAAAATCTGTGAAGTGGATCTAGTGATCAGTTTGAATATTCCATTTGAAACACTTAAA
GATCGTCTCAGCCGCCGTTGGATTCACCCTCCTAGCGGAAGGGTATATAACCTGGACTTC
AATCCACCTCATGTACATGGTATTGATGACGTCACTGGTGAACCATTAGTCCAGCAGGAG
GATGATAAACCCGAAGCAGTTGCTGCCAGGCTAAGACAGTACAAAGACGTGGCAAAGCCA
GTCATTGAATTATACAAGAGCCGAGGAGTGCTCCACCAATTTTCCGGAACGGAGACGAAC
AAAATCTGGCCCTACGTTTACACACTTTTCTCAAACAAGATCACACCTATTCAGTCCAAA
GAAGCATATTGA
Protein Properties
Number of Residues 223
Molecular Weight 25267.83
Theoretical pI 8.394
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Adenylate kinase isoenzyme 4, mitochondrial
MASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEK
SLLVPDHVITRLMMSELENRRGQHWLLDGFPRTLGQAEALDKICEVDLVISLNIPFETLK
DRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKP
VIELYKSRGVLHQFSGTETNKIWPYVYTLFSNKITPIQSKEAY
GenBank ID Protein 189069342
UniProtKB/Swiss-Prot ID P27144
UniProtKB/Swiss-Prot Entry Name KAD4_HUMAN
PDB IDs
GenBank Gene ID AK313611
GeneCard ID AK4
GenAtlas ID AK4
HGNC ID HGNC:363
References
General References Not Available