| Identification |
|---|
| HMDB Protein ID
| CDBP00555 |
| Secondary Accession Numbers
| Not Available |
| Name
| Adenylate kinase isoenzyme 4, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- ATP-AMP transphosphorylase
- Adenylate kinase 3-like
|
| Gene Name
| AK4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in ATP binding |
| Specific Function
| Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. May also be active with GTP (By similarity).
|
| GO Classification
|
| Biological Process |
| response to organic nitrogen |
| ATP metabolic process |
| AMP metabolic process |
| GTP metabolic process |
| response to organic cyclic compound |
| Cellular Component |
| mitochondrial matrix |
| Function |
| phosphotransferase activity, phosphate group as acceptor |
| transferase activity |
| adenylate kinase activity |
| transferase activity, transferring phosphorus-containing groups |
| kinase activity |
| nucleobase, nucleoside, nucleotide kinase activity |
| nucleoside binding |
| purine nucleoside binding |
| adenyl nucleotide binding |
| adenyl ribonucleotide binding |
| atp binding |
| binding |
| catalytic activity |
| nucleotide kinase activity |
| Molecular Function |
| ATP binding |
| GTP binding |
| adenylate kinase activity |
| nucleoside triphosphate adenylate kinase activity |
| Process |
| nitrogen compound metabolic process |
| cellular nitrogen compound metabolic process |
| nucleobase, nucleoside, nucleotide and nucleic acid metabolic process |
| metabolic process |
|
| Cellular Location
|
- Mitochondrion matrix
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| 1 |
| Locus
| 1p31.3 |
| SNPs
| AK4 |
| Gene Sequence
|
>672 bp
ATGGCTTCCAAACTCCTGCGCGCGGTCATCCTCGGGCCGCCCGGCTCGGGCAAGGGCACC
GTGTGCCAGAGGATCGCCCAGAACTTTGGTCTCCAGCATCTCTCCAGCGGCCACTTCTTG
CGGGAGAACATCAAGGCCAGCACCGAAGTTGGTGAGATGGCAAAGCAGTATATAGAGAAA
AGTCTTTTGGTTCCAGACCATGTGATCACACGCCTAATGATGTCCGAGTTGGAGAACAGG
CGTGGCCAGCACTGGCTCCTTGATGGTTTTCCTAGGACATTAGGACAAGCCGAAGCCCTG
GACAAAATCTGTGAAGTGGATCTAGTGATCAGTTTGAATATTCCATTTGAAACACTTAAA
GATCGTCTCAGCCGCCGTTGGATTCACCCTCCTAGCGGAAGGGTATATAACCTGGACTTC
AATCCACCTCATGTACATGGTATTGATGACGTCACTGGTGAACCATTAGTCCAGCAGGAG
GATGATAAACCCGAAGCAGTTGCTGCCAGGCTAAGACAGTACAAAGACGTGGCAAAGCCA
GTCATTGAATTATACAAGAGCCGAGGAGTGCTCCACCAATTTTCCGGAACGGAGACGAAC
AAAATCTGGCCCTACGTTTACACACTTTTCTCAAACAAGATCACACCTATTCAGTCCAAA
GAAGCATATTGA
|
| Protein Properties |
|---|
| Number of Residues
| 223 |
| Molecular Weight
| 25267.83 |
| Theoretical pI
| 8.394 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Adenylate kinase isoenzyme 4, mitochondrial
MASKLLRAVILGPPGSGKGTVCQRIAQNFGLQHLSSGHFLRENIKASTEVGEMAKQYIEK
SLLVPDHVITRLMMSELENRRGQHWLLDGFPRTLGQAEALDKICEVDLVISLNIPFETLK
DRLSRRWIHPPSGRVYNLDFNPPHVHGIDDVTGEPLVQQEDDKPEAVAARLRQYKDVAKP
VIELYKSRGVLHQFSGTETNKIWPYVYTLFSNKITPIQSKEAY
|
| External Links |
|---|
| GenBank ID Protein
| 189069342 |
| UniProtKB/Swiss-Prot ID
| P27144 |
| UniProtKB/Swiss-Prot Entry Name
| KAD4_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AK313611 |
| GeneCard ID
| AK4 |
| GenAtlas ID
| AK4 |
| HGNC ID
| HGNC:363 |
| References |
|---|
| General References
| Not Available |