Cannabis Compound Database: Showing Protein GTP:AMP phosphotransferase, mitochondrial (CDBP00542)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP00542

Secondary Accession Numbers

Not Available

Name

GTP:AMP phosphotransferase, mitochondrial

Description

Not Available

Synonyms

AK 3
Adenylate kinase 3
Adenylate kinase 3 alpha-like 1

Gene Name

AK3

Protein Type

Enzyme

Biological Properties

General Function

Involved in ATP binding

Specific Function

Not Available

GO Classification

Biological Process
blood coagulation
AMP metabolic process
AMP phosphorylation
GTP metabolic process
ITP metabolic process
UTP metabolic process
Cellular Component
mitochondrial matrix
Function
transferase activity, transferring phosphorus-containing groups
kinase activity
nucleobase, nucleoside, nucleotide kinase activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
binding
catalytic activity
nucleotide kinase activity
phosphotransferase activity, phosphate group as acceptor
transferase activity
adenylate kinase activity
Molecular Function
ATP binding
GTP binding
adenylate kinase activity
nucleoside triphosphate adenylate kinase activity
nucleotide kinase activity
Process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process

Cellular Location

Mitochondrion matrix

Pathways

Name	SMPDB/Pathwhiz	KEGG
Pyrimidine Metabolism
Beta Ureidopropionase Deficiency		Not Available
UMP Synthase Deficiency (Orotic Aciduria)		Not Available
Dihydropyrimidinase Deficiency		Not Available
MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)		Not Available

Gene Properties

Chromosome Location

Locus

9p24.1

SNPs

AK3

Gene Sequence

>684 bp
ATGGGGGCGTCGGGGCGGCTGCTGCGAGCGGTGATCATGGGGGCCCCGGGCTCGGGCAAG
GGCACCGTGTCGTCCCGCATCACTACACACTTCGAGCTGAAGCACCTCTCCCGCGGGGAC
CTGCTCCGGGACAACATGCTGCGGGGCACAGAAATTGGCGTGTTAGCCCAGGCTTTCATT
GACCAAGGGAAACTCATCCCAGATTATGTCACGACTCGGCTGGCCCTTCATGAGCTGAAA
AACCTCACCCAGTATAGCTGGCTGTTGGATGGTTTTCCAAGGACACTTCCACAGGCAGAA
GCCCTAGATAGAGCTTATCAGATCGACACAGTGATTAACCTGAATGTGCCCTTTGAGGTC
ATTAAACAACGCCTTACTGCTCGCTGGATTCATCCCGCCAGTGGCCGAGTCTATAACATT
GAATTCAACCCTCCCAAAACTGTGGGCATTGATGACCTGACTGGGGAGCCTCTCATTCAG
CGTGAGGATGATAAACCAGAGACGGTTATCAAGAGACTAAAGGCTTATGAAGACCAAACA
AAGCCAGTCCTGGAATATTACCAGAAAAAAGGGGTGTTGGAAACATTCTCCGGAACAGAA
ACCAACAAGATTTGGCCCTATGTATATGCTTTCCTACAAACTAAAGTTCCACAAAGAAGC
CAGAAAGCTTCAGTTACTCCATGA

Protein Properties

Number of Residues

227

Molecular Weight

21013.93

Theoretical pI

9.522

Pfam Domain Function

ADK (PF00406 )
ADK_lid (PF05191 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>GTP:AMP phosphotransferase, mitochondrial
MGASARLLRAVIMGAPGSGKGTVSSRITTHFELKHLSSGDLLRDNMLRGTEIGVLAKAFI
DQGKLIPDDVMTRLALHELKNLTQYSWLLDGFPRTLPQAEALDRAYQIDTVINLNVPFEV
IKQRLTARWIHPASGRVYNIEFNPPKTVGIDDLTGEPLIQREDDKPETVIKRLKAYEDQT
KPVLEYYQKKGVLETFSGTETNKIWPYVYAFLQTKVPQRSQKASVTP

External Links

GenBank ID Protein

6518533

UniProtKB/Swiss-Prot ID

Q9UIJ7

UniProtKB/Swiss-Prot Entry Name

KAD3_HUMAN

PDB IDs