| Identification |
|---|
| HMDB Protein ID
| CDBP00524 |
| Secondary Accession Numbers
| Not Available |
| Name
| Acylphosphatase-1 |
| Description
| Not Available |
| Synonyms
|
- Acylphosphatase, erythrocyte isozyme
- Acylphosphatase, organ-common type isozyme
- Acylphosphate phosphohydrolase 1
|
| Gene Name
| ACYP1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in acylphosphatase activity |
| Specific Function
| Its physiological role is not yet clear.
|
| GO Classification
|
| Biological Process |
| phosphate-containing compound metabolic process |
| Function |
| catalytic activity |
| acylphosphatase activity |
| hydrolase activity |
| hydrolase activity, acting on acid anhydrides |
| hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides |
| Molecular Function |
| acylphosphatase activity |
|
| Cellular Location
|
- Cytoplasmic
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Pyruvate Metabolism |    |  | | Leigh Syndrome |    | Not Available | | Pyruvate Decarboxylase E1 Component Deficiency (PDHE1 Deficiency) |    | Not Available | | Pyruvate Dehydrogenase Complex Deficiency |    | Not Available | | Primary hyperoxaluria II, PH2 |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 14 |
| Locus
| 14q24.3 |
| SNPs
| ACYP1 |
| Gene Sequence
|
>300 bp
ATGGCAGAAGGAAACACCCTGATATCAGTGGATTATGAAATTTTTGGGAAGGTGCAAGGG
GTGTTTTTCCGTAAGCATACTCAGGCTGAGGGTAAAAAGCTGGGATTGGTAGGCTGGGTC
CAGAACACTGACCGGGGCACAGTGCAAGGACAATTGCAAGGTCCCATCTCCAAGGTGCGT
CATATGCAGGAATGGCTTGAAACAAGAGGAAGTCCTAAATCACACATCGACAAAGCAAAC
TTCAACAATGAAAAAGTCATCTTGAAGTTGGATTACTCAGACTTCCAAATTGTAAAATAA
|
| Protein Properties |
|---|
| Number of Residues
| 99 |
| Molecular Weight
| 11260.84 |
| Theoretical pI
| 9.312 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Acylphosphatase-1
MAEGNTLISVDYEIFGKVQGVFFRKHTQAEGKKLGLVGWVQNTDRGTVQGQLQGPISKVR
HMQEWLETRGSPKSHIDKANFNNEKVILKLDYSDFQIVK
|
| External Links |
|---|
| GenBank ID Protein
| 4885693 |
| UniProtKB/Swiss-Prot ID
| P07311 |
| UniProtKB/Swiss-Prot Entry Name
| ACYP1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AC007055 |
| GeneCard ID
| ACYP1 |
| GenAtlas ID
| ACYP1 |
| HGNC ID
| HGNC:179 |
| References |
|---|
| General References
| Not Available |