Showing Protein Ribonuclease pancreatic (CDBP00442)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 3 compounds
Identification
HMDB Protein ID CDBP00442
Secondary Accession Numbers Not Available
Name Ribonuclease pancreatic
Description Not Available
Synonyms
  1. HP-RNase
  2. RIB-1
  3. RNase 1
  4. RNase A
  5. RNase UpI-1
  6. Ribonuclease 1
  7. Ribonuclease A
Gene Name RNASE1
Protein Type Enzyme
Biological Properties
General Function Involved in nucleic acid binding
Specific Function Endonuclease that catalyzes the cleavage of RNA on the 3' side of pyrimidine nucleotides. Acts on single stranded and double stranded RNA
GO Classification
Function
hydrolase activity, acting on ester bonds
binding
catalytic activity
hydrolase activity
nucleic acid binding
nuclease activity
endonuclease activity
endoribonuclease activity
endoribonuclease activity, producing 3'-phosphomonoesters
pancreatic ribonuclease activity
Cellular Location
  1. Secreted
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 14q11.2
SNPs RNASE1
Gene Sequence 
>471 bp
ATGGCTCTGGAGAAGTCTCTTGTCCGGCTCCTTCTGCTTGTCCTGATACTGCTGGTGCTG
GGCTGGGTCCAGCCTTCCCTGGGCAAGGAATCCCGGGCCAAGAAATTCCAGCGGCAGCAT
ATGGACTCAGACAGTTCCCCCAGCAGCAGCTCCACCTACTGTAACCAAATGATGAGGCGC
CGGAATATGACACAGGGGCGGTGCAAACCAGTGAACACCTTTGTGCACGAGCCCCTGGTA
GATGTCCAGAATGTCTGTTTCCAGGAAAAGGTCACCTGCAAGAACGGGCAGGGCAACTGC
TACAAGAGCAACTCCAGCATGCACATCACAGACTGCCGCCTGACAAACGGCTCCAGGTAC
CCCAACTGTGCATACCGGACCAGCCCGAAGGAGAGACACATCATTGTGGCCTGTGAAGGG
AGCCCATATGTGCCAGTCCACTTTGATGCTTCTGTGGAGGACTCTACCTAA
Protein Properties
Number of Residues 156
Molecular Weight 17644.1
Theoretical pI 8.94
Pfam Domain Function
Signals
  • ["1-28"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>Ribonuclease pancreatic
MALEKSLVRLLLLVLILLVLGWVQPSLGKESRAKKFQRQHMDSDSSPSSSSTYCNQMMRR
RNMTQGRCKPVNTFVHEPLVDVQNVCFQEKVTCKNGQGNCYKSNSSMHITDCRLTNGSRY
PNCAYRTSPKERHIIVACEGSPYVPVHFDASVEDST
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID P07998
UniProtKB/Swiss-Prot Entry Name RNAS1_HUMAN
PDB IDs
GenBank Gene ID D26129
GeneCard ID RNASE1
GenAtlas ID RNASE1
HGNC ID HGNC:10044
References
General References Not Available