| Identification |
|---|
| HMDB Protein ID
| CDBP00380 |
| Secondary Accession Numbers
| Not Available |
| Name
| Enoyl-CoA hydratase, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- Enoyl-CoA hydratase 1
- SCEH
- Short-chain enoyl-CoA hydratase
|
| Gene Name
| ECHS1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Straight-chain enoyl-CoA thioesters from C4 up to at least C16 are processed, although with decreasing catalytic rate.
|
| GO Classification
|
| Biological Process |
| fatty acid beta-oxidation |
| Cellular Component |
| mitochondrial matrix |
| Function |
| catalytic activity |
| Molecular Function |
| enoyl-CoA hydratase activity |
| Process |
| metabolic process |
|
| Cellular Location
|
- Mitochondrion matrix
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | fatty acid beta-oxidation | Not Available | Not Available | | Fatty acid elongation | Not Available |  | | Butanoate metabolism | Not Available |  | | Butyrate Metabolism |    | | | Fatty Acid Elongation In Mitochondria |    | |
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| 10q26.2-q26.3 |
| SNPs
| ECHS1 |
| Gene Sequence
|
>873 bp
ATGGCCGCCCTGCGTGTCCTGCTGTCCTGCGTCCGCGGCCCGCTGAGGCCCCCGGTTCGC
TGTCCCGCCTGGCGTCCCTTCGCCTCGGGTGCTAACTTTGAGTACATCATCGCAGAAAAA
AGAGGGAAGAATAACACCGTGGGGTTGATCCAACTGAACCGCCCCAAGGCCCTCAATGCA
CTTTGCGATGGCCTGATTGACGAGCTCAACCAGGCCCTGAAGACCTTCGAGGAGGACCCG
GCCGTGGGGGCCATTGTCCTCACCGGCGGGGATAAGGCCTTTGCAGCTGGAGCTGATATC
AAGGAAATGCAGAACCTGAGTTTCCAGGACTGTTACTCCAGCAAGTTCTTGAAGCACTGG
GACCACCTCACCCAGGTCAAGAAGCCAGTCATCGCTGCTGTCAATGGCTATGCCTTTGGC
GGGGGCTGTGAGCTTGCCATGATGTGTGATATCATCTATGCCGGTGAGAAGGCCCAGTTT
GCACAGCCGGAGATCTTAATAGGAACCATCCCAGGTGCGGGCGGCACCCAGAGACTCACC
CGTGCTGTTGGGAAGTCGCTGGCGATGGAGATGGTCCTCACTGGTGACCGGATCTCAGCC
CAGGACGCCAAGCAAGCAGGTCTTGTCAGCAAGATTTGTCCTGTTGAGACACTGGTGGAA
GAAGCCATCCAGTGTGCAGAAAAAATTGCCAGCAATTCTAAAATTGTAGTAGCGATGGCC
AAAGAATCAGTGAATGCAGCTTTTGAAATGACATTAACAGAAGGAAGTAAGTTGGAGAAG
AAACTCTTTTATTCAACCTTTGCCACTGATGACCGGAAAGAAGGGATGACCGCGTTTGTG
GAAAAGAGAAAGGCCAACTTCAAAGACCAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 290 |
| Molecular Weight
| 31387.085 |
| Theoretical pI
| 8.073 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Enoyl-CoA hydratase, mitochondrial
MAALRVLLSCVRGPLRPPVRCPAWRPFASGANFEYIIAEKRGKNNTVGLIQLNRPKALNA
LCDGLIDELNQALKTFEEDPAVGAIVLTGGDKAFAAGADIKEMQNLSFQDCYSSKFLKHW
DHLTQVKKPVIAAVNGYAFGGGCELAMMCDIIYAGEKAQFAQPEILIGTIPGAGGTQRLT
RAVGKSLAMEMVLTGDRISAQDAKQAGLVSKICPVETLVEEAIQCAEKIASNSKIVVAMA
KESVNAAFEMTLTEGSKLEKKLFYSTFATDDRKEGMTAFVEKRKANFKDQ
|
| External Links |
|---|
| GenBank ID Protein
| 55664849 |
| UniProtKB/Swiss-Prot ID
| P30084 |
| UniProtKB/Swiss-Prot Entry Name
| ECHM_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AL360181 |
| GeneCard ID
| ECHS1 |
| GenAtlas ID
| ECHS1 |
| HGNC ID
| HGNC:3151 |
| References |
|---|
| General References
| Not Available |