Cannabis Compound Database: Showing Protein 6-phosphogluconolactonase (CDBP00321)

Identification Biological properties Gene properties Protein properties External links References XML Show 5 compounds

Identification

HMDB Protein ID

CDBP00321

Secondary Accession Numbers

Not Available

Name

6-phosphogluconolactonase

Description

Not Available

Synonyms

6PGL

Gene Name

PGLS

Protein Type

Enzyme

Biological Properties

General Function

Involved in 6-phosphogluconolactonase activity

Specific Function

Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate.

GO Classification

Biological Process
pentose-phosphate shunt
pentose-phosphate shunt, oxidative branch
Cellular Component
cytosol
Function
hydrolase activity, acting on ester bonds
catalytic activity
hydrolase activity
6-phosphogluconolactonase activity
carboxylesterase activity
Molecular Function
6-phosphogluconolactonase activity
monosaccharide binding
Process
monosaccharide metabolic process
hexose metabolic process
glucose metabolic process
glucose catabolic process
metabolic process
primary metabolic process
pentose-phosphate shunt
carbohydrate metabolic process
small molecule metabolic process
alcohol metabolic process

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
Pentose Phosphate Pathway
Glucose-6-phosphate dehydrogenase deficiency		Not Available
Ribose-5-phosphate isomerase deficiency		Not Available
Transaldolase deficiency		Not Available
Warburg Effect		Not Available

Gene Properties

Chromosome Location

Locus

19p13.2

SNPs

PGLS

Gene Sequence

>777 bp
ATGGCCGCGCCGGCCCCGGGCCTCATCTCGGTGTTCTCGAGTTCCCAGGAGCTGGGTGCG
GCGCTAGCGCAGCTGGTGGCCCAGCGCGCAGCATGCTGCCTGGCAGGGGCCCGCGCCCGT
TTCGCGCTCGGCCTGTCGGGCGGGAGCCTCGTCTCGATGCTAGCCCGCGAGCTACCCGCC
GCCGTCGCCCCTGCCGGGCCAGCTAGCTTAGCGCGCTGGACGCTGGGCTTCTGCGACGAG
CGCCTCGTGCCCTTCGATCACGCCGAGAGCACGTACGGCCTCTACCGGACGCATCTTCTC
TCCAGACTGCCGATCCCAGAAAGCCAGGTGATCACCATTAACCCCGAGCTGCCTGTGGAG
GAGGCGGCTGAGGACTACGCCAAGAAGCTGAGACAGGCATTCCAAGGGGACTCCATCCCG
GTTTTCGACCTGCTGATCCTGGGGGTGGGCCCCGATGGTCACACCTGCTCACTCTTCCCA
GACCACCCCCTCCTACAGGAGCGGGAGAAGATTGTGGCTCCCATCAGTGACTCCCCGAAG
CCACCGCCACAGCGTGTGACCCTCACACTACCTGTCCTGAATGCAGCACGAACTGTCATC
TTTGTGGCAACTGGAGAAGGCAAGGCAGCTGTTCTGAAGCGCATTTTGGAGGACCAGGAG
GAAAACCCGCTGCCCGCCGCCCTGGTCCAGCCCCACACCGGGAAACTGTGCTGGTTCTTG
GACGAGGCGGCCGCCCGCCTCCTGACCGTGCCCTTCGAGAAGCATTCCACTTTGTAG

Protein Properties

Number of Residues

258

Molecular Weight

27546.495

Theoretical pI

6.048

Pfam Domain Function

Not Available

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>6-phosphogluconolactonase
MAAPAPGLISVFSSSQELGAALAQLVAQRAACCLAGARARFALGLSGGSLVSMLARELPA
AVAPAGPASLARWTLGFCDERLVPFDHAESTYGLYRTHLLSRLPIPESQVITINPELPVE
EAAEDYAKKLRQAFQGDSIPVFDLLILGVGPDGHTCSLFPDHPLLQEREKIVAPISDSPK
PPPQRVTLTLPVLNAARTVIFVATGEGKAAVLKRILEDQEENPLPAALVQPHTGKLCWFL
DEAAARLLTVPFEKHSTL

External Links

GenBank ID Protein

6912586

UniProtKB/Swiss-Prot ID

O95336

UniProtKB/Swiss-Prot Entry Name

6PGL_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_012088.2

GeneCard ID