Cannabis Compound Database: Showing Protein Branched-chain-amino-acid aminotransferase, cytosolic (CDBP00295)

Identification Biological properties Gene properties Protein properties External links References XML Show 9 compounds

Identification

HMDB Protein ID

CDBP00295

Secondary Accession Numbers

Not Available

Name

Branched-chain-amino-acid aminotransferase, cytosolic

Description

Not Available

Synonyms

BCAT(c)
Protein ECA39

Gene Name

BCAT1

Protein Type

Enzyme

Biological Properties

General Function

Involved in catalytic activity

Specific Function

Catalyzes the first reaction in the catabolism of the essential branched chain amino acids leucine, isoleucine, and valine.

GO Classification

Biological Process
branched-chain amino acid biosynthetic process
G1/S transition of mitotic cell cycle
branched-chain amino acid catabolic process
cellular nitrogen compound metabolic process
cell proliferation
Cellular Component
cytosol
Function
catalytic activity
branched-chain-amino-acid transaminase activity
transferase activity
transferase activity, transferring nitrogenous groups
transaminase activity
Molecular Function
branched-chain-amino-acid transaminase activity
L-isoleucine transaminase activity
L-leucine transaminase activity
L-valine transaminase activity
Process
branched chain family amino acid metabolic process
metabolic process
cellular metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
Valine, leucine and isoleucine biosynthesis	Not Available
2-Oxocarboxylic acid metabolism	Not Available
Valine, Leucine and Isoleucine Degradation
Beta-Ketothiolase Deficiency		Not Available
2-Methyl-3-Hydroxybutryl CoA Dehydrogenase Deficiency		Not Available

Gene Properties

Chromosome Location

Locus

12p12.1

SNPs

BCAT1

Gene Sequence

>1161 bp
ATGAAGGATTGCAGTAACGGATGCTCCGCAGAGTGTACCGGAGAAGGAGGATCAAAAGAG
GTGGTGGGGACTTTTAAGGCTAAAGACCTAATAGTCACACCAGCTACCATTTTAAAGGAA
AAACCAGACCCCAATAATCTGGTTTTTGGAACTGTGTTCACGGATCATATGCTGACGGTG
GAGTGGTCCTCAGAGTTTGGATGGGAGAAACCTCATATCAAGCCTCTTCAGAACCTGTCA
TTGCACCCTGGCTCATCAGCTTTGCACTATGCAGTGGAATTATTTGAAGGATTGAAGGCA
TTTCGAGGAGTAGATAATAAAATTCGACTGTTTCAGCCAAACCTCAACATGGATAGAATG
TATCGCTCTGCTGTGAGGGCAACTCTGCCGGTATTTGACAAAGAAGAGCTCTTAGAGTGT
ATTCAACAGCTTGTGAAATTGGATCAAGAATGGGTCCCATATTCAACATCTGCTAGTCTG
TATATTCGTCCTACATTCATTGGAACTGAGCCTTCTCTTGGAGTCAAGAAGCCTACCAAA
GCCCTGCTCTTTGTACTCTTGAGCCCAGTGGGACCTTATTTTTCAAGTGGAACCTTTAAT
CCAGTGTCCCTGTGGGCCAATCCCAAGTATGTAAGAGCCTGGAAAGGTGGAACTGGGGAC
TGCAAGATGGGAGGGAATTACGGCTCATCTCTTTTTGCCCAATGTGAAGCAGTAGATAAT
GGGTGTCAGCAGGTCCTGTGGCTCTATGGAGAGGACCATCAGATCACTGAAGTGGGAACT
ATGAATCTTTTTCTTTACTGGATAAATGAAGATGGAGAAGAAGAACTGGCAACTCCTCCA
CTAGATGGCATCATTCTTCCAGGAGTGACAAGGCGGTGCATTCTGGACCTGGCACATCAG
TGGGGTGAATTTAAGGTGTCAGAGAGATACCTCACCATGGATGACTTGACAACAGCCCTG
GAGGGGAACAGAGTGAGAGAGATGTTTGGCTCTGGTACAGCCTGTGTTGTTTGCCCAGTT
TCTGATATACTGTACAAAGGCGAGACAATACACATTCCAACTATGGAGAATGGTCCTAAG
CTGGCAAGCCGCATCTTGAGCAAATTAACTGATATCCAGTATGGAAGAGAAGAGAGCGAC
TGGACAATTGTGCTATCCTGA

Protein Properties

Number of Residues

386

Molecular Weight

38644.77

Theoretical pI

4.99

Pfam Domain Function

Aminotran_4 (PF01063 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Branched-chain-amino-acid aminotransferase, cytosolic
MKDCSNGCSAECTGEGGSKEVVGTFKAKDLIVTPATILKEKPDPNNLVFGTVFTDHMLTV
EWSSEFGWEKPHIKPLQNLSLHPGSSALHYAVELFEGLKAFRGVDNKIRLFQPNLNMDRM
YRSAVRATLPVFDKEELLECIQQLVKLDQEWVPYSTSASLYIRPTFIGTEPSLGVKKPTK
ALLFVLLSPVGPYFSSGTFNPVSLWANPKYVRAWKGGTGDCKMGGNYGSSLFAQCEAVDN
GCQQVLWLYGEDHQITEVGTMNLFLYWINEDGEEELATPPLDGIILPGVTRRCILDLAHQ
WGEFKVSERYLTMDDLTTALEGNRVREMFGSGTACVVCPVSDILYKGETIHIPTMENGPK
LASRILSKLTDIQYGREESDWTIVLS

External Links

GenBank ID Protein

38176287

UniProtKB/Swiss-Prot ID

P54687

UniProtKB/Swiss-Prot Entry Name

BCAT1_HUMAN

PDB IDs