Cannabis Compound Database: Showing Protein Arginase-1 (CDBP00292)

Identification Biological properties Gene properties Protein properties External links References XML Show 6 compounds

Identification

HMDB Protein ID

CDBP00292

Secondary Accession Numbers

Not Available

Name

Arginase-1

Description

Not Available

Synonyms

Liver-type arginase
Type I arginase

Gene Name

ARG1

Protein Type

Enzyme

Biological Properties

General Function

Involved in arginase activity

Specific Function

Not Available

GO Classification

Biological Process
response to selenium ion
response to methylmercury
arginine catabolic process
response to vitamin E
cellular response to dexamethasone stimulus
urea cycle
response to vitamin A
cellular response to glucagon stimulus
cellular response to hydrogen peroxide
cellular response to transforming growth factor beta stimulus
collagen biosynthetic process
mammary gland involution
maternal process involved in female pregnancy
positive regulation of endothelial cell proliferation
response to cadmium ion
protein homotrimerization
response to zinc ion
regulation of L-arginine import
response to amino acid stimulus
response to amine stimulus
liver development
response to axon injury
response to drug
cellular response to lipopolysaccharide
response to herbicide
lung development
response to manganese ion
Cellular Component
cytosol
neuronal cell body
extracellular space
neuron projection
Function
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
ion binding
cation binding
metal ion binding
binding
catalytic activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amidines
arginase activity
Molecular Function
manganese ion binding
arginase activity
Process
metabolic process
arginine metabolic process
cellular metabolic process
glutamine family amino acid metabolic process
cellular amino acid and derivative metabolic process
cellular amino acid metabolic process

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
Arginine and Proline Metabolism
Urea Cycle
Amoebiasis	Not Available
Prolidase Deficiency (PD)		Not Available
Arginine: Glycine Amidinotransferase Deficiency (AGAT Deficiency)		Not Available

Gene Properties

Chromosome Location

Locus

6q23

SNPs

ARG1

Gene Sequence

>969 bp
ATGAGCGCCAAGTCCAGAACCATAGGGATTATTGGAGCTCCTTTCTCAAAGGGACAGCCA
CGAGGAGGGGTGGAAGAAGGCCCTACAGTATTGAGAAAGGCTGGTCTGCTTGAGAAACTT
AAAGAACAAGAGTGTGATGTGAAGGATTATGGGGACCTGCCCTTTGCTGACATCCCTAAT
GACAGTCCCTTTCAAATTGTGAAGAATCCAAGGTCTGTGGGAAAAGCAAGCGAGCAGCTG
GCTGGCAAGGTGGCACAAGTCAAGAAGAACGGAAGAATCAGCCTGGTGCTGGGCGGAGAC
CACAGTTTGGCAATTGGAAGCATCTCTGGCCATGCCAGGGTCCACCCTGATCTTGGAGTC
ATCTGGGTGGATGCTCACACTGATATCAACACTCCACTGACAACCACAAGTGGAAACTTG
CATGGACAACCTGTATCTTTCCTCCTGAAGGAACTAAAAGGAAAGATTCCCGATGTGCCA
GGATTCTCCTGGGTGACTCCCTGTATATCTGCCAAGGATATTGTGTATATTGGCTTGAGA
GACGTGGACCCTGGGGAACACTACATTTTGAAAACTCTAGGCATTAAATACTTTTCAATG
ACTGAAGTGGACAGACTAGGAATTGGCAAGGTGATGGAAGAAACACTCAGCTATCTACTA
GGAAGAAAGAAAAGGCCAATTCATCTAAGTTTTGATGTTGACGGACTGGACCCATCTTTC
ACACCAGCTACTGGCACACCAGTCGTGGGAGGTCTGACATACAGAGAAGGTCTCTACATC
ACAGAAGAAATCTACAAAACAGGGCTACTCTCAGGATTAGATATAATGGAAGTGAACCCA
TCCCTGGGGAAGACACCAGAAGAAGTAACTCGAACAGTGAACACAGCAGTTGCAATAACC
TTGGCTTGTTTCGGACTTGCTCGGGAGGGTAATCACAAGCCTATTGACTACCTTAACCCA
CCTAAGTAA

Protein Properties

Number of Residues

322

Molecular Weight

34734.655

Theoretical pI

7.217

Pfam Domain Function

Arginase (PF00491 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Arginase-1
MSAKSRTIGIIGAPFSKGQPRGGVEEGPTVLRKAGLLEKLKEQECDVKDYGDLPFADIPN
DSPFQIVKNPRSVGKASEQLAGKVAEVKKNGRISLVLGGDHSLAIGSISGHARVHPDLGV
IWVDAHTDINTPLTTTSGNLHGQPVSFLLKELKGKIPDVPGFSWVTPCISAKDIVYIGLR
DVDPGEHYILKTLGIKYFSMTEVDRLGIGKVMEETLSYLLGRKKRPIHLSFDVDGLDPSF
TPATGTPVVGGLTYREGLYITEEIYKTGLLSGLDIMEVNPSLGKTPEEVTRTVNTAVAIT
LACFGLAREGNHKPIDYLNPPK

External Links

GenBank ID Protein

178995

UniProtKB/Swiss-Prot ID

P05089

UniProtKB/Swiss-Prot Entry Name

ARGI1_HUMAN

PDB IDs