| Identification |
|---|
| HMDB Protein ID
| CDBP00263 |
| Secondary Accession Numbers
| Not Available |
| Name
| Phosphoglycerate mutase 1 |
| Description
| Not Available |
| Synonyms
|
- BPG-dependent PGAM 1
- PGAM-B
- Phosphoglycerate mutase isozyme B
|
| Gene Name
| PGAM1 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in catalytic activity |
| Specific Function
| Interconversion of 3- and 2-phosphoglycerate with 2,3-bisphosphoglycerate as the primer of the reaction. Can also catalyze the reaction of EC 5.4.2.4 (synthase) and EC 3.1.3.13 (phosphatase), but with a reduced activity.
|
| GO Classification
|
| Biological Process |
| respiratory burst |
| small molecule metabolic process |
| regulation of glycolysis |
| glycolysis |
| gluconeogenesis |
| regulation of pentose-phosphate shunt |
| Cellular Component |
| cytosol |
| Function |
| catalytic activity |
| isomerase activity |
| intramolecular transferase activity |
| intramolecular transferase activity, phosphotransferases |
| Molecular Function |
| bisphosphoglycerate 2-phosphatase activity |
| bisphosphoglycerate mutase activity |
| phosphoglycerate mutase activity |
| Process |
| glycolysis |
| metabolic process |
| small molecule metabolic process |
| alcohol metabolic process |
| monosaccharide metabolic process |
| hexose metabolic process |
| glucose metabolic process |
| glucose catabolic process |
|
| Cellular Location
|
Not Available
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Glycolysis / Gluconeogenesis | Not Available |  | | Glycine, serine and threonine metabolism | Not Available |  | | Glycolysis |    | | | Glycogenosis, Type VII. Tarui disease |    | Not Available | | Fanconi-bickel syndrome |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 10 |
| Locus
| 10q25.3 |
| SNPs
| PGAM1 |
| Gene Sequence
|
>765 bp
ATGGCCGCCTACAAACTGGTGCTGATCCGGCACGGCGAGAGCGCATGGAACCTGGAGAAC
CGCTTCAGCGGCTGGTACGACGCCGACCTGAGCCCGGCGGGCCACGAGGAGGCGAAGCGC
GGCGGGCAGGCGCTACGAGATGCTGGCTATGAGTTTGACATCTGCTTCACCTCAGTGCAG
AAGAGAGCGATCCGGACCCTCTGGACAGTGCTAGATGCCATTGATCAGATGTGGCTGCCA
GTGGTGAGGACTTGGCGCCTCAATGAGCGGCACTATGGGGGTCTAACCGGTCTCAATAAA
GCAGAAACTGCTGCAAAGCATGGTGAGGCCCAGGTGAAGATCTGGAGGCGCTCCTATGAT
GTCCCACCACCTCCGATGGAGCCCGACCATCCTTTCTACAGCAACATCAGTAAGGATCGC
AGGTATGCAGACCTCACAGAAGATCAGCTACCCTCCTGTGAGAGTCTGAAGGATACTATT
GCCAGAGCTCTGCCCTTCTGGAATGAAGAAATAGTTCCCCAGATCAAGGAGGGGAAACGT
GTACTGATTGCAGCCCATGGCAACAGCCTCCGGGGCATTGTCAAGCATCTGGAGGGTCTC
TCTGAAGAGGCTATCATGGAGCTGAACCTGCCGACTGGTATTCCCATTGTCTATGAATTG
GACAAGAACTTGAAGCCTATCAAGCCCATGCAGTTTCTGGGGGATGAAGAGACGGTGCGC
AAAGCCATGGAAGCTGTGGCTGCCCAGGGCAAGGCCAAGAAGTGA
|
| Protein Properties |
|---|
| Number of Residues
| 254 |
| Molecular Weight
| 28803.675 |
| Theoretical pI
| 7.182 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Phosphoglycerate mutase 1
MAAYKLVLIRHGESAWNLENRFSGWYDADLSPAGHEEAKRGGQALRDAGYEFDICFTSVQ
KRAIRTLWTVLDAIDQMWLPVVRTWRLNERHYGGLTGLNKAETAAKHGEAQVKIWRRSYD
VPPPPMEPDHPFYSNISKDRRYADLTEDQLPSCESLKDTIARALPFWNEEIVPQIKEGKR
VLIAAHGNSLRGIVKHLEGLSEEAIMELNLPTGIPIVYELDKNLKPIKPMQFLGDEETVR
KAMEAVAAQGKAKK
|
| External Links |
|---|
| GenBank ID Protein
| 9956014 |
| UniProtKB/Swiss-Prot ID
| P18669 |
| UniProtKB/Swiss-Prot Entry Name
| PGAM1_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AY007118 |
| GeneCard ID
| PGAM1 |
| GenAtlas ID
| PGAM1 |
| HGNC ID
| HGNC:8888 |
| References |
|---|
| General References
| Not Available |