| Identification |
|---|
| HMDB Protein ID
| CDBP00250 |
| Secondary Accession Numbers
| Not Available |
| Name
| Methylmalonyl-CoA epimerase, mitochondrial |
| Description
| Not Available |
| Synonyms
|
- DL-methylmalonyl-CoA racemase
|
| Gene Name
| MCEE |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Amino acid transport and metabolism |
| Specific Function
| Not Available |
| GO Classification
|
| Biological Process |
| L-methylmalonyl-CoA metabolic process |
| short-chain fatty acid catabolic process |
| fatty acid beta-oxidation |
| Cellular Component |
| mitochondrial matrix |
| Molecular Function |
| methylmalonyl-CoA epimerase activity |
|
| Cellular Location
|
- Cytoplasm
- Mitochondrion (Probable)
|
| Pathways
|
| Name | SMPDB/Pathwhiz | KEGG | | Glyoxylate and dicarboxylate metabolism | Not Available |  | | Propanoate Metabolism |    |  | | Malonic Aciduria |    | Not Available | | Methylmalonic Aciduria Due to Cobalamin-Related Disorders |    | Not Available | | Malonyl-coa decarboxylase deficiency |    | Not Available |
|
| Gene Properties |
|---|
| Chromosome Location
| 2 |
| Locus
| 2p13.3 |
| SNPs
| MCEE |
| Gene Sequence
|
>531 bp
ATGGCGCGGGTGCTGAAGGCTGCAGCCGCGAATGCCGTAGGGCTTTTTTCCAGACTTCAA
GCTCCCATTCCAACAGTAAGAGCTTCTTCCACATCACAGCCCTTGGATCAAGTGACAGGT
TCTGTGTGGAACCTGGGTCGACTCAACCATGTAGCCATAGCAGTGCCAGATTTGGAAAAG
GCTGCAGCATTTTATAAGAATATTCTGGGGGCCCAGGTAAGTGAAGCGGTCCCTCTTCCT
GAACATGGAGTATCTGTTGTTTTTGTCAACCTGGGAAATACCAAGATGGAACTGCTTCAT
CCATTGGGACGTGACAGTCCAATTGCAGGTTTTCTGCAGAAAAACAAGGCTGGAGGAATG
CATCACATCTGCATCGAGGTGGATAATATTAATGCAGCTGTGATGGATTTGAAAAAAAAG
AAGATCCGCAGTCTAAGTGAAGAGGTCAAAATAGGAGCACATGGAAAACCAGTGATTTTT
CTCCATCCTAAAGACTGTGGTGGAGTCCTTGTGGAACTGGAGCAAGCTTGA
|
| Protein Properties |
|---|
| Number of Residues
| 176 |
| Molecular Weight
| 18748.755 |
| Theoretical pI
| 9.081 |
| Pfam Domain Function
|
|
| Signals
|
Not Available
|
|
Transmembrane Regions
|
Not Available
|
| Protein Sequence
|
>Methylmalonyl-CoA epimerase, mitochondrial
MARVLKAAAANAVGLFSRLQAPIPTVRASSTSQPLDQVTGSVWNLGRLNHVAIAVPDLEK
AAAFYKNILGAQVSEAVPLPEHGVSVVFVNLGNTKMELLHPLGRDSPIAGFLQKNKAGGM
HHICIEVDNINAAVMDLKKKKIRSLSEEVKIGAHGKPVIFLHPKDCGGVLVELEQA
|
| External Links |
|---|
| GenBank ID Protein
| 62822200 |
| UniProtKB/Swiss-Prot ID
| Q96PE7 |
| UniProtKB/Swiss-Prot Entry Name
| MCEE_HUMAN |
| PDB IDs
|
|
| GenBank Gene ID
| AC007881 |
| GeneCard ID
| MCEE |
| GenAtlas ID
| MCEE |
| HGNC ID
| HGNC:16732 |
| References |
|---|
| General References
| Not Available |