Cannabis Compound Database: Showing Protein Glucosamine-6-phosphate isomerase 1 (CDBP00205)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP00205

Secondary Accession Numbers

Not Available

Name

Glucosamine-6-phosphate isomerase 1

Description

Not Available

Synonyms

GNPDA 1
GlcN6P deaminase 1
Glucosamine-6-phosphate deaminase 1
Oscillin

Gene Name

GNPDA1

Protein Type

Enzyme

Biological Properties

General Function

Involved in carbohydrate metabolic process

Specific Function

Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo (By similarity).

GO Classification

Biological Process
N-acetylglucosamine metabolic process
glucosamine catabolic process
single fertilization
carbohydrate metabolic process
generation of precursor metabolites and energy
Cellular Component
cytoplasm
Function
catalytic activity
isomerase activity
intramolecular oxidoreductase activity
intramolecular oxidoreductase activity, interconverting aldoses and ketoses
glucosamine-6-phosphate deaminase activity
Molecular Function
glucosamine-6-phosphate deaminase activity
hydrolase activity
Process
alcohol metabolic process
monosaccharide metabolic process
amino sugar metabolic process
glucosamine metabolic process
n-acetylglucosamine metabolic process
metabolic process
primary metabolic process
carbohydrate metabolic process
small molecule metabolic process

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
Amino sugar and nucleotide sugar metabolism	Not Available
Amino Sugar Metabolism
Sialuria or French Type Sialuria		Not Available
Salla Disease/Infantile Sialic Acid Storage Disease		Not Available
Tay-Sachs Disease		Not Available

Gene Properties

Chromosome Location

Locus

5q21

SNPs

GNPDA1

Gene Sequence

>870 bp
ATGAAGCTCATCATCCTGGAGCACTATTCTCAGGCGAGCGAGTGGGCGGCTAAATACATC
AGGAACCGTATCATCCAGTTTAACCCAGGGCCAGAGAAGTACTTCACCCTGGGGCTCCCC
ACTGGGAGTACCCCACTTGGCTGCTACAAGAAGCTGATTGAATACTATAAGAATGGGGAC
CTGTCCTTTAAATATGTGAAGACCTTCAACATGGATGAGTACGTGGGCCTTCCTCGAGAC
CACCCGGAGAGTTACCACTCCTTCATGTGGAACAACTTCTTCAAGCACATTGACATCCAC
CCAGAAAACACCCACATTCTGGATGGGAATGCAGTCGACCTACAGGCAGAATGTGATGCC
TTTGAAGAGAAGATCAAGGCTGCAGGTGGGATCGAGCTATTTGTTGGAGGCATCGGCCCT
GATGGACACATTGCCTTCAACGAGCCAGGCTCCAGTCTGGTGTCCAGGACCCGTGTGAAG
ACGCTGGCCATGGATACCATCCTGGCCAATGCTAGGTTCTTCGATGGAGAACTCACCAAG
GTGCCCACCATGGCCTTGACGGTGGGGGTGGGCACTGTCATGGATGCTAGAGAGGTGATG
ATCCTTATCACAGGTGCTCACAAGGCATTTGCTCTGTACAAGGCCATCGAGGAGGGAGTG
AACCACATGTGGACCGTGTCTGCCTTCCAGCAGCATCCCCGCACCGTGTTTGTGTGTGAC
GAGGATGCCACCTTGGAGCTGAAAGTGAAGACTGTCAAGTATTTCAAAGGTTTAATGCTT
GTTCATAACAAGTTGGTGGACCCCTTGTACAGTATCAAAGAGAAAGAAACTGAGAAAAGC
CAATCTTCGAAGAAACCATACAGCGATTAG

Protein Properties

Number of Residues

289

Molecular Weight

32668.29

Theoretical pI

6.912

Pfam Domain Function

Glucosamine_iso (PF01182 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Glucosamine-6-phosphate isomerase 1
MKLIILEHYSQASEWAAKYIRNRIIQFNPGPEKYFTLGLPTGSTPLGCYKKLIEYYKNGD
LSFKYVKTFNMDEYVGLPRDHPESYHSFMWNNFFKHIDIHPENTHILDGNAVDLQAECDA
FEEKIKAAGGIELFVGGIGPDGHIAFNEPGSSLVSRTRVKTLAMDTILANARFFDGELTK
VPTMALTVGVGTVMDAREVMILITGAHKAFALYKAIEEGVNHMWTVSAFQQHPRTVFVCD
EDATLELKVKTVKYFKGLMLVHNKLVDPLYSIKEKETEKSQSSKKPYSD

External Links

GenBank ID Protein

Not Available

UniProtKB/Swiss-Prot ID

P46926

UniProtKB/Swiss-Prot Entry Name

GNPI1_HUMAN

PDB IDs