Cannabis Compound Database: Showing Protein Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial (CDBP00171)

Identification Biological properties Gene properties Protein properties External links References XML Show 4 compounds

Identification

HMDB Protein ID

CDBP00171

Secondary Accession Numbers

Not Available

Name

Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial

Description

Not Available

Synonyms

ETF dehydrogenase
ETF-QO
ETF-ubiquinone oxidoreductase
Electron-transferring-flavoprotein dehydrogenase

Gene Name

ETFDH

Protein Type

Enzyme

Biological Properties

General Function

Involved in electron-transferring-flavoprotein dehydrogenase activity

Specific Function

Accepts electrons from ETF and reduces ubiquinone.

GO Classification

Biological Process
response to oxidative stress
fatty acid beta-oxidation using acyl-CoA dehydrogenase
respiratory electron transport chain
Cellular Component
mitochondrial matrix
integral to mitochondrial inner membrane
Function
catalytic activity
oxidoreductase activity, acting on the ch-nh group of donors
oxidoreductase activity, acting on the ch-nh group of donors, quinone or similar compound as acceptor
electron-transferring-flavoprotein dehydrogenase activity
oxidoreductase activity
Molecular Function
flavin adenine dinucleotide binding
ubiquinone binding
electron carrier activity
metal ion binding
4 iron, 4 sulfur cluster binding
electron-transferring-flavoprotein dehydrogenase activity
oxidoreductase activity, oxidizing metal ions with flavin as acceptor
Process
metabolic process
oxidation reduction

Cellular Location

Mitochondrion inner membrane

Pathways

Not Available

Gene Properties

Chromosome Location

Locus

4q32-q35

SNPs

ETFDH

Gene Sequence

>1854 bp
ATGCTGGTGCCGCTAGCCAAGCTGTCCTGCCTGGCATATCAGTGCTTTCATGCCTTAAAA
ATTAAGAAAAATTATCTACCTCTATGTGCTACAAGATGGTCTTCAACTTCTACTGTGCCT
CGAATTACTACCCATTATACTATTTATCCCCGGGATAAGGACAAGAGATGGGAAGGAGTG
AACATGGAAAGGTTTGCAGAAGAAGCAGATGTTGTAATAGTTGGTGCAGGCCCTGCAGGG
CTCTCTGCAGCTGTTCGTCTAAAACAGTTGGCTGTGGCACATGAAAAGGACATCCGTGTG
TGTCTAGTGGAGAAAGCTGCCCAGATAGGAGCTCATACTCTCTCAGGGGCTTGCCTTGAT
CCAGGTGCTTTTAAAGAACTCTTCCCAGACTGGAAAGAGAAGGGGGCTCCACTTAACACT
CCTGTAACAGAAGACAGATTTGGAATTTTAACAGAGAAATACAGAATTCCTGTGCCAATT
CTTCCAGGGCTTCCAATGAATAATCATGGCAATTACATTGTACGCTTGGGACATTTAGTG
AGCTGGATGGGCGAACAAGCAGAAGCCCTTGGTGTTGAAGTATACCCTGGTTATGCAGCT
GCTGAGGTCCTTTTTCATGATGATGGTAGTGTAAAAGGAATTGCCACTAACGATGTAGGG
ATACAAAAGGATGGTGCACCAAAGGCAACATTTGAGAGAGGACTGGAACTACATGCTAAA
GTCACAATTTTTGCAGAAGGTTGCCATGGACATCTAGCCAAGCAACTATATAAGAAGTTT
GATTTGAGAGCAAATTGTGAACCTCAAACCTACGGGATTGGACTGAAGGAGTTATGGGTT
ATTGATGAAAAGAACTGGAAACCTGGGAGAGTAGATCACACTGTTGGTTGGCCCTTGGAC
AGACATACCTATGGAGGATCTTTCCTCTATCATTTGAATGAAGGTGAACCCCTAGTAGCT
CTTGGTCTTGTGGTTGGTCTAGACTATCAGAATCCATACCTGAGTCCATTTAGAGAGTTC
CAAAGGTGGAAACACCATCCTAGCATTCGGCCAACCTTGGAAGGTGGAAAAAGGATTGCA
TACGGAGCCAGAGCTCTCAATGAAGGTGGCTTTCAGTCTATACCAAAACTCACCTTTCCT
GGTGGTTTACTAATTGGTTGTAGTCCTGGTTTTATGAATGTTCCCAAGATCAAAGGTACT
CACACAGCAATGAAAAGTGGAATTTTAGCAGCAGAATCTATTTTTAATCAACTAACTAGT
GAAAATCTCCAATCAAAGACAATAGGACTCCATGTAACTGAATATGAGGACAATTTGAAG
AACTCATGGGTATGGAAAGAGCTATATTCTGTTAGAAATATAAGACCGTCCTGCCACGGA
GTACTGGGTGTATATGGAGGGATGATTTACACTGGAATCTTTTACTGGATATTGAGAGGA
ATGGAGCCGTGGACTCTGAAACATAAAGGTTCTGACTTTGAACGGCTCAAGCCAGCCAAG
GATTGCACACCTATTGAGTATCCAAAACCCGATGGACAGATCAGTTTTGACCTCTTGTCA
TCTGTGGCTCTGAGTGGTACTAATCATGAACATGACCAGCCGGCACACTTAACCTTAAGG
GATGACAGTATACCTGTAAATAGAAATCTGTCGATATATGATGGGCCCGAGCAGCGATTC
TGTCCTGCAGGAGTTTATGAATTTGTACCTGTGGAACAAGGTGATGGATTTCGGTTACAG
ATAAATGCTCAGAACTGTGTACATTGTAAAACATGTGATATTAAAGATCCAAGTCAGAAT
ATTAACTGGGTGGTACCTGAAGGTGGAGGAGGACCTGCTTACAATGGAATGTAA

Protein Properties

Number of Residues

617

Molecular Weight

68494.96

Theoretical pI

7.554

Pfam Domain Function

ETF_QO (PF05187 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial
MLVPLAKLSCLAYQCFHALKIKKNYLPLCATRWSSTSTVPRITTHYTIYPRDKDKRWEGV
NMERFAEEADVVIVGAGPAGLSAAVRLKQLAVAHEKDIRVCLVEKAAQIGAHTLSGACLD
PGAFKELFPDWKEKGAPLNTPVTEDRFGILTEKYRIPVPILPGLPMNNHGNYIVRLGHLV
SWMGEQAEALGVEVYPGYAAAEVLFHDDGSVKGIATNDVGIQKDGAPKATFERGLELHAK
VTIFAEGCHGHLAKQLYKKFDLRANCEPQTYGIGLKELWVIDEKNWKPGRVDHTVGWPLD
RHTYGGSFLYHLNEGEPLVALGLVVGLDYQNPYLSPFREFQRWKHHPSIRPTLEGGKRIA
YGARALNEGGFQSIPKLTFPGGLLIGCSPGFMNVPKIKGTHTAMKSGILAAESIFNQLTS
ENLQSKTIGLHVTEYEDNLKNSWVWKELYSVRNIRPSCHGVLGVYGGMIYTGIFYWILRG
MEPWTLKHKGSDFERLKPAKDCTPIEYPKPDGQISFDLLSSVALSGTNHEHDQPAHLTLR
DDSIPVNRNLSIYDGPEQRFCPAGVYEFVPVEQGDGFRLQINAQNCVHCKTCDIKDPSQN
INWVVPEGGGGPAYNGM

External Links

GenBank ID Protein

119703746

UniProtKB/Swiss-Prot ID

Q16134

UniProtKB/Swiss-Prot Entry Name

ETFD_HUMAN

PDB IDs

Not Available

GenBank Gene ID

NM_004453.2

GeneCard ID