| Identification |
| HMDB Protein ID
| CDBP00170 |
| Secondary Accession Numbers
| Not Available |
| Name
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5 |
| Description
| Not Available |
| Synonyms
|
- CI-13kD-B
- Complex I subunit B13
- Complex I-13kD-B
- NADH-ubiquinone oxidoreductase 13 kDa-B subunit
|
| Gene Name
| NDUFA5 |
| Protein Type
| Enzyme |
| Biological Properties |
| General Function
| Involved in oxidoreductase activity, acting on NADH or NADPH |
| Specific Function
| Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone |
| GO Classification
|
| Component |
| membrane |
| cell part |
| organelle membrane |
| organelle inner membrane |
| mitochondrial inner membrane |
| Function |
| catalytic activity |
| oxidoreductase activity |
| oxidoreductase activity, acting on nadh or nadph |
| Process |
| metabolic process |
| generation of precursor metabolites and energy |
| electron transport chain |
| respiratory electron transport chain |
| cellular metabolic process |
|
| Cellular Location
|
- Peripheral membrane protein
- Mitochondrion inner membrane
- Matrix side
|
| Pathways
|
Not Available
|
| Gene Properties |
| Chromosome Location
| Chromosome:7 |
| Locus
| 7q32 |
| SNPs
| NDUFA5 |
| Gene Sequence
|
>351 bp
ATGGCGGGTGTGCTGAAGAAGACCACTGGCCTTGTGGGATTGGCTGTGTGCAATACTCCT
CACGAGAGGCTAAGAATATTGTACACAAAGATTCTTGATGTTCTTGAGGAAATCCCTAAA
AATGCAGCATATAGAAAGTATACAGAACAGATTACAAATGAGAAGCTGGCTATGGTTAAA
GCGGAACCAGATGTTAAAAAATTAGAAGACCAACTTCAAGGCGGTCAATTAGAAGAGGTG
ATTCTTCAGGCTGAACATGAACTAAATCTGGCAAGAAAAATGAGGGAATGGAAACTATGG
GAGCCATTAGTGGAAGAGCCTCCTGCCGATCAGTGGAAATGGCCAATATAA
|
| Protein Properties |
| Number of Residues
| 116 |
| Molecular Weight
| 13458.6 |
| Theoretical pI
| 5.81 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 5
MAGVLKKTTGLVGLAVCNTPHERLRILYTKILDVLEEIPKNAAYRKYTEQITNEKLAMVK
AEPDVKKLEDQLQGGQLEEVILQAEHELNLARKMREWKLWEPLVEEPPADQWKWPI
|
| External Links |
| GenBank ID Protein
| 37674403 |
| UniProtKB/Swiss-Prot ID
| Q16718 |
| UniProtKB/Swiss-Prot Entry Name
| NDUA5_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AC073323 |
| GeneCard ID
| NDUFA5 |
| GenAtlas ID
| NDUFA5 |
| HGNC ID
| HGNC:7688 |
| References |
| General References
| Not Available |