Showing Protein NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3 (CDBP00167)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 5 compounds
Identification
HMDB Protein ID CDBP00167
Secondary Accession Numbers Not Available
Name NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
Description Not Available
Synonyms
  1. CI-B12
  2. Complex I-B12
  3. NADH-ubiquinone oxidoreductase B12 subunit
Gene Name NDUFB3
Protein Type Enzyme
Biological Properties
General Function Involved in NADH dehydrogenase (ubiquinone) activity
Specific Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
GO Classification
Component
organelle
membrane-bounded organelle
intracellular membrane-bounded organelle
mitochondrion
Function
catalytic activity
nadh dehydrogenase activity
nadh dehydrogenase (quinone) activity
nadh dehydrogenase (ubiquinone) activity
oxidoreductase activity
oxidoreductase activity, acting on nadh or nadph
Cellular Location
  1. Single-pass membrane protein
  2. Mitochondrion inner membrane
  3. Matrix side
Pathways
Gene Properties
Chromosome Location Chromosome:2
Locus 2q31.3
SNPs NDUFB3
Gene Sequence 
>297 bp
ATGGCCCATGAACATGGACATGAGCATGGACATCATAAAATGGAACTTCCAGATTATAGA
CAATGGAAGATAGAAGGGACACCATTAGAAACTATCCAGAAGAAGCTGGCTGCAAAAGGG
CTAAGGGATCCATGGGGCCGCAATGAAGCTTGGAGATACATGGGTGGCTTTGCAAAGAGT
GTTTCCTTTTCTGATGTATTCTTTAAAGGATTCAAATGGGGATTTGCTGCATTTGTGGTA
GCTGTAGGAGCTGAATATTACCTGGAGTCCCTGAATAAAGATAAGAAGCATCACTGA
Protein Properties
Number of Residues 98
Molecular Weight 11401.9
Theoretical pI 9.73
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["66-88"]
Protein Sequence 
>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 3
MAHEHGHEHGHHKMELPDYRQWKIEGTPLETIQKKLAAKGLRDPWGRNEAWRYMGGFAKS
VSFSDVFFKGFKWGFAAFVVAVGAEYYLESLNKDKKHH
GenBank ID Protein 3098338
UniProtKB/Swiss-Prot ID O43676
UniProtKB/Swiss-Prot Entry Name NDUB3_HUMAN
PDB IDs Not Available
GenBank Gene ID AF035839
GeneCard ID NDUFB3
GenAtlas ID NDUFB3
HGNC ID HGNC:7698
References
General References Not Available