| Identification |
|---|
| HMDB Protein ID
| CDBP00144 |
| Secondary Accession Numbers
| Not Available |
| Name
| NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4 |
| Description
| Not Available |
| Synonyms
|
- CI-B15
- Complex I-B15
- NADH-ubiquinone oxidoreductase B15 subunit
|
| Gene Name
| NDUFB4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in NADH dehydrogenase (ubiquinone) activity |
| Specific Function
| Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone |
| GO Classification
|
| Component |
| mitochondrion |
| organelle |
| membrane-bounded organelle |
| intracellular membrane-bounded organelle |
| Function |
| oxidoreductase activity, acting on nadh or nadph |
| catalytic activity |
| nadh dehydrogenase activity |
| nadh dehydrogenase (quinone) activity |
| nadh dehydrogenase (ubiquinone) activity |
| oxidoreductase activity |
|
| Cellular Location
|
- Single-pass membrane protein
- Mitochondrion inner membrane
- Matrix side
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:3 |
| Locus
| 3q13.33 |
| SNPs
| NDUFB4 |
| Gene Sequence
|
>390 bp
ATGTCGTTCCCAAAGTATAAGCCGTCGAGCCTGCGCACTCTGCCTGAGACCCTCGACCCA
GCCGAATACAACATATCTCCGGAAACCCGGCGGGCGCAAGCCGAGCGGTTGGCCATAAGA
GCCCAGCTGAAACGAGAGTACCTGCTTCAGTACAACGATCCCAACCGCCGAGGGCTCATC
GAAAATCCTGCCTTGCTTCGTTGGGCCTATGCAAGAACAATAAATGTCTATCCTAATTTC
AGACCCACTCCTAAAAACTCACTCATGGGAGCTCTGTGTGGATTTGGGCCCCTCATCTTC
ATTTATTATATTATCAAAACTGAGAGGGATAGGAAAGAAAAACTTATCCAGGAAGGAAAA
TTGGATCGAACATTTCACCTCTCATATTAA
|
| Protein Properties |
|---|
| Number of Residues
| 129 |
| Molecular Weight
| 15208.4 |
| Theoretical pI
| 10.24 |
| Pfam Domain Function
|
Not Available |
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>NADH dehydrogenase [ubiquinone] 1 beta subcomplex subunit 4
MSFPKYKPSSLRTLPETLDPAEYNISPETRRAQAERLAIRAQLKREYLLQYNDPNRRGLI
ENPALLRWAYARTINVYPNFRPTPKNSLMGALCGFGPLIFIYYIIKTERDRKEKLIQEGK
LDRTFHLSY
|
| External Links |
|---|
| GenBank ID Protein
| Not Available |
| UniProtKB/Swiss-Prot ID
| O95168 |
| UniProtKB/Swiss-Prot Entry Name
| NDUB4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF044957 |
| GeneCard ID
| NDUFB4 |
| GenAtlas ID
| NDUFB4 |
| HGNC ID
| HGNC:7699 |
| References |
|---|
| General References
| Not Available |