Showing Protein NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial (CDBP00132)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 5 compounds
Identification
HMDB Protein ID CDBP00132
Secondary Accession Numbers Not Available
Name NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
Description Not Available
Synonyms
  1. CI-18 kDa
  2. CI-AQDQ
  3. Complex I-18 kDa
  4. Complex I-AQDQ
  5. NADH-ubiquinone oxidoreductase 18 kDa subunit
Gene Name NDUFS4
Protein Type Enzyme
Biological Properties
General Function Involved in oxidoreductase activity, acting on NADH or NADPH
Specific Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
GO Classification
Component
membrane
cell part
organelle membrane
organelle inner membrane
mitochondrial inner membrane
Function
catalytic activity
oxidoreductase activity
oxidoreductase activity, acting on nadh or nadph
Process
metabolic process
generation of precursor metabolites and energy
electron transport chain
cellular metabolic process
Cellular Location
  1. Peripheral membrane protein
  2. Mitochondrion inner membrane
  3. Matrix side
Pathways
Gene Properties
Chromosome Location Chromosome:5
Locus 5q11.1
SNPs NDUFS4
Gene Sequence 
>528 bp
ATGGCGGCGGTCTCAATGTCAGTGGTACTGAGGCAGACGTTGTGGCGGAGAAGGGCAGTG
GCTGTAGCTGCCCTTTCCGTTTCCAGGGTTCCGACCAGGTCGTTGAGGACTTCCACATGG
AGATTGGCACAGGACCAGACTCAAGACACACAACTCATAACAGTTGATGAAAAATTGGAT
ATCACTACTTTAACTGGCGTTCCAGAAGAGCATATAAAAACTAGAAAAGTCAGGATCTTT
GTTCCTGCTCGCAATAACATGCAGTCTGGAGTAAACAACACAAAGAAATGGAAGATGGAG
TTTGATACCAGGGAGCGATGGGAAAATCCTTTGATGGGTTGGGCATCAACGGCTGATCCC
TTATCCAACATGGTTCTAACCTTCAGTACTAAAGAAGATGCAGTTTCCTTTGCAGAAAAA
AATGGATGGAGCTATGACATTGAAGAGAGGAAGGTTCCAAAACCCAAGTCCAAGTCTTAT
GGTGCAAACTTTTCTTGGAACAAAAGAACAAGAGTATCCACAAAATAG
Protein Properties
Number of Residues 175
Molecular Weight 20107.8
Theoretical pI 11.02
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial
MAAVSMSVVLRQTLWRRRAVAVAALSVSRVPTRSLRTSTWRLAQDQTQDTQLITVDEKLD
ITTLTGVPEEHIKTRKVRIFVPARNNMQSGVNNTKKWKMEFDTRERWENPLMGWASTADP
LSNMVLTFSTKEDAVSFAEKNGWSYDIEERKVPKPKSKSYGANFSWNKRTRVSTK
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID O43181
UniProtKB/Swiss-Prot Entry Name NDUS4_HUMAN
PDB IDs Not Available
GenBank Gene ID AF020351
GeneCard ID NDUFS4
GenAtlas ID NDUFS4
HGNC ID HGNC:7711
References
General References Not Available