| Identification |
|---|
| HMDB Protein ID
| CDBP00126 |
| Secondary Accession Numbers
| Not Available |
| Name
| NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4 |
| Description
| Not Available |
| Synonyms
|
- CI-MLRQ
- Complex I-MLRQ
- NADH-ubiquinone oxidoreductase MLRQ subunit
|
| Gene Name
| NDUFA4 |
| Protein Type
| Enzyme |
| Biological Properties |
|---|
| General Function
| Involved in NADH dehydrogenase (ubiquinone) activity |
| Specific Function
| Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed to be not involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone |
| GO Classification
|
Not Available
|
| Cellular Location
|
- Peripheral membrane protein
- Mitochondrion inner membrane
- Matrix side
|
| Pathways
|
Not Available
|
| Gene Properties |
|---|
| Chromosome Location
| Chromosome:7 |
| Locus
| 7p21.3 |
| SNPs
| NDUFA4 |
| Gene Sequence
|
>246 bp
ATGCTCCGCCAGATCATCGGTCAGGCCAAGAAGCATCCGAGCTTGATCCCCCTCTTTGTA
TTTATTGGAACTGGAGCTACTGGAGCAACACTGTATCTCTTGCGTCTGGCATTGTTCAAT
CCAGATGTTTGTTGGGACAGAAATAACCCAGAGCCCTGGAACAAACTGGGTCCCAATGAT
CAATACAAGTTCTACTCAGTGAATGTGGATTACAGCAAGCTGAAGAAGGAACGTCCAGAT
TTCTAA
|
| Protein Properties |
|---|
| Number of Residues
| 81 |
| Molecular Weight
| 9369.8 |
| Theoretical pI
| 9.84 |
| Pfam Domain Function
|
|
| Signals
|
|
|
Transmembrane Regions
|
|
| Protein Sequence
|
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 4
MLRQIIGQAKKHPSLIPLFVFIGTGATGATLYLLRLALFNPDVCWDRNNPEPWNKLGPND
QYKFYSVNVDYSKLKKERPDF
|
| External Links |
|---|
| GenBank ID Protein
| 6456749 |
| UniProtKB/Swiss-Prot ID
| O00483 |
| UniProtKB/Swiss-Prot Entry Name
| NDUA4_HUMAN |
| PDB IDs
|
Not Available |
| GenBank Gene ID
| AF201077 |
| GeneCard ID
| NDUFA4 |
| GenAtlas ID
| NDUFA4 |
| HGNC ID
| HGNC:7687 |
| References |
|---|
| General References
| Not Available |