Showing Protein NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12 (CDBP00119)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 5 compounds
Identification
HMDB Protein ID CDBP00119
Secondary Accession Numbers Not Available
Name NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
Description Not Available
Synonyms
  1. 13 kDa differentiation-associated protein
  2. CI-B17.2
  3. CIB17.2
  4. Complex I-B17.2
  5. NADH-ubiquinone oxidoreductase subunit B17.2
Gene Name NDUFA12
Protein Type Enzyme
Biological Properties
General Function Involved in NADH dehydrogenase (ubiquinone) activity
Specific Function Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone
GO Classification
Component
membrane
cell part
Function
nadh dehydrogenase (quinone) activity
nadh dehydrogenase (ubiquinone) activity
oxidoreductase activity
oxidoreductase activity, acting on nadh or nadph
catalytic activity
nadh dehydrogenase activity
electron carrier activity
Cellular Location
  1. Peripheral membrane protein
  2. Mitochondrion inner membrane
  3. Matrix side
Pathways
Gene Properties
Chromosome Location Chromosome:1
Locus 12q22
SNPs NDUFA12
Gene Sequence 
>438 bp
ATGGAGTTAGTGCAGGTCCTGAAACGCGGGCTGCAGCAGATCACCGGCCACGGCGGTCTC
CGAGGCTATCTACGGGTTTTTTTCAGGACAAATGATGCGAAGGTTGGTACATTAGTGGGG
GAAGACAAATATGGAAACAAATACTATGAAGACAACAAGCAATTTTTTGGCCGTCACCGA
TGGGTTGTATATACTACTGAAATGAATGGCAAAAACACATTCTGGGATGTGGATGGAAGC
ATGGTGCCTCCTGAATGGCATCGTTGGCTTCACAGTATGACTGATGATCCTCCAACAACA
AAACCACTTACTGCTCGTAAATTCATTTGGACGAACCATAAATTCAACGTGACTGGCACC
CCAGAACAATATGTACCTTATTCTACCACTAGAAAGAAGATTCAGGAGTGGATCCCACCT
TCAACACCTTACAAGTAA
Protein Properties
Number of Residues 145
Molecular Weight 17114.4
Theoretical pI 10.1
Pfam Domain Function
Signals
  • ["None"]
Transmembrane Regions
  • ["None"]
Protein Sequence 
>NADH dehydrogenase [ubiquinone] 1 alpha subcomplex subunit 12
MELVQVLKRGLQQITGHGGLRGYLRVFFRTNDAKVGTLVGEDKYGNKYYEDNKQFFGRHR
WVVYTTEMNGKNTFWDVDGSMVPPEWHRWLHSMTDDPPTTKPLTARKFIWTNHKFNVTGT
PEQYVPYSTTRKKIQEWIPPSTPYK
GenBank ID Protein Not Available
UniProtKB/Swiss-Prot ID Q9UI09
UniProtKB/Swiss-Prot Entry Name NDUAC_HUMAN
PDB IDs Not Available
GenBank Gene ID AF217092
GeneCard ID NDUFA12
GenAtlas ID NDUFA12
HGNC ID HGNC:23987
References
General References Not Available