Showing Protein Nucleoside diphosphate kinase, mitochondrial (CDBP00103)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 13 compounds
Identification
HMDB Protein ID CDBP00103
Secondary Accession Numbers Not Available
Name Nucleoside diphosphate kinase, mitochondrial
Description Not Available
Synonyms
  1. NDK
  2. NDP kinase, mitochondrial
  3. NDPKD
  4. Nucleoside diphosphate kinase D
  5. nm23-H4
Gene Name NME4
Protein Type Enzyme
Biological Properties
General Function Involved in nucleoside diphosphate kinase activity
Specific Function Major role in the synthesis of nucleoside triphosphates other than ATP (By similarity).
GO Classification
Biological Process
nucleobase-containing small molecule interconversion
CTP biosynthetic process
GTP biosynthetic process
UTP biosynthetic process
nucleoside metabolic process
Cellular Component
mitochondrial inner membrane
mitochondrial intermembrane space
Function
nucleoside diphosphate kinase activity
binding
catalytic activity
phosphotransferase activity, phosphate group as acceptor
transferase activity
transferase activity, transferring phosphorus-containing groups
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
adenyl ribonucleotide binding
atp binding
Molecular Function
metal ion binding
ATP binding
nucleoside diphosphate kinase activity
Process
ctp biosynthetic process
pyrimidine nucleotide metabolic process
pyrimidine nucleoside triphosphate biosynthetic process
pyrimidine nucleotide biosynthetic process
pyrimidine ribonucleoside triphosphate biosynthetic process
utp biosynthetic process
purine nucleotide metabolic process
purine nucleotide biosynthetic process
purine nucleoside triphosphate biosynthetic process
purine ribonucleoside triphosphate biosynthetic process
gtp biosynthetic process
metabolic process
nitrogen compound metabolic process
cellular nitrogen compound metabolic process
nucleobase, nucleoside, nucleotide and nucleic acid metabolic process
nucleobase, nucleoside and nucleotide metabolic process
nucleoside phosphate metabolic process
nucleotide metabolic process
Cellular Location
  1. Mitochondrion intermembrane space
Pathways
Gene Properties
Chromosome Location 16
Locus 16p13.3
SNPs NME4
Gene Sequence 
>564 bp
ATGGGCGGCCTCTTCTGGCGCTCCGCGCTGCGGGGGCTGCGCTGCGGCCCGCGGGCCCCG
GGCCCGAGCCTGCTAGTGCGCCACGGCTCGGGAGGGCCCTCCTGGACCCGGGAGCGGACC
CTGGTGGCGGTGAAGCCCGATGGCGTGCAACGGCGGCTCGTTGGGGACGTGATCCAGCGC
TTTGAGAGGCGGGGCTTCACGCTGGTGGGGATGAAGATGCTGCAGGCACCAGAGAGCGTC
CTTGCCGAGCACTACCAGGACCTGCGGAGGAAGCCCTTCTACCCTGCCCTCATCCGCTAC
ATGAGCTCTGGGCCTGTGGTGGCCATGGTCTGGGAAGGGTACAATGTCGTCCGCGCCTCG
AGGGCCATGATTGGACACACCGACTCGGCTGAGGCTGCCCCAGGAACCATAAGGGGTGAC
TTCAGCGTCCACATCAGCAGGAATGTCATCCACGCCAGCGACTCCGTGGAGGGGGCCCAG
CGGGAGATCCAGCTGTGGTTCCAGAGCAGTGAGCTGGTGAGCTGGGCAGACGGGGGCCAG
CACAGCAGCATCCACCCAGCCTGA
Protein Properties
Number of Residues 187
Molecular Weight 20658.45
Theoretical pI 10.293
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Nucleoside diphosphate kinase, mitochondrial
MGGLFWRSALRGLRCGPRAPGPSLLVRHGSGGPSWTRERTLVAVKPDGVQRRLVGDVIQR
FERRGFTLVGMKMLQAPESVLAEHYQDLRRKPFYPALIRYMSSGPVVAMVWEGYNVVRAS
RAMIGHTDSAEAAPGTIRGDFSVHISRNVIHASDSVEGAQREIQLWFQSSELVSWADGGQ
HSSIHPA
GenBank ID Protein 14336697
UniProtKB/Swiss-Prot ID O00746
UniProtKB/Swiss-Prot Entry Name NDKM_HUMAN
PDB IDs
GenBank Gene ID AE006463
GeneCard ID NME4
GenAtlas ID NME4
HGNC ID HGNC:7852
References
General References Not Available