Showing Protein Medium-chain specific acyl-CoA dehydrogenase, mitochondrial (CDBP00101)

IdentificationBiological propertiesGene propertiesProtein propertiesExternal linksReferencesXMLShow 9 compounds
Identification
HMDB Protein ID CDBP00101
Secondary Accession Numbers Not Available
Name Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
Description Not Available
Synonyms
  1. MCAD
Gene Name ACADM
Protein Type Enzyme
Biological Properties
General Function Involved in acyl-CoA dehydrogenase activity
Specific Function This enzyme is specific for acyl chain lengths of 4 to 16.
GO Classification
Biological Process
protein homotetramerization
carnitine metabolic process, CoA-linked
fatty acid beta-oxidation using acyl-CoA dehydrogenase
cardiac muscle cell differentiation
carnitine biosynthetic process
glycogen biosynthetic process
medium-chain fatty acid catabolic process
post-embryonic development
regulation of gluconeogenesis
response to cold
response to copper ion
liver development
response to drug
response to nutrient
response to starvation
response to glucocorticoid stimulus
Cellular Component
mitochondrial membrane
mitochondrial matrix
axon
Function
binding
catalytic activity
nucleoside binding
purine nucleoside binding
adenyl nucleotide binding
oxidoreductase activity
fad or fadh2 binding
oxidoreductase activity, acting on the ch-ch group of donors
acyl-coa dehydrogenase activity
Molecular Function
flavin adenine dinucleotide binding
fatty-acyl-CoA binding
identical protein binding
isomerase activity
medium-chain-acyl-CoA dehydrogenase activity
Process
metabolic process
oxidation reduction
Cellular Location
  1. Mitochondrion matrix
Pathways
Gene Properties
Chromosome Location 1
Locus 1p31
SNPs ACADM
Gene Sequence 
>1266 bp
ATGGCAGCGGGGTTCGGGCGATGCTGCAGGGTCCTGAGAAGTATTTCTCGTTTTCATTGG
AGATCACAGCATACAAAAGCCAATCGACAACGTGAACCAGGATTAGGATTTAGTTTTGAG
TTCACCGAACAGCAGAAAGAATTTCAAGCTACTGCTCGTAAATTTGCCAGAGAGGAAATC
ATCCCAGTGGCTGCAGAATATGATAAAACTGGTGAATATCCAGTCCCCCTAATTAGAAGA
GCCTGGGAACTTGGTTTAATGAACACACACATTCCAGAGAACTGTGGAGGTCTTGGACTT
GGAACTTTTGATGCTTGTTTAATTAGTGAAGAATTGGCTTATGGATGTACAGGGGTTCAG
ACTGCTATTGAAGGAAATTCTTTGGGGCAAATGCCTATTATTATTGCTGGAAATGATCAA
CAAAAGAAGAAGTATTTGGGGAGAATGACTGAGGAGCCATTGATGTGTGCTTATTGTGTA
ACAGAACCTGGAGCAGGCTCTGATGTAGCTGGTATAAAGACCAAAGCAGAAAAGAAAGGA
GATGAGTATATTATTAATGGTCAGAAGATGTGGATAACCAACGGAGGAAAAGCTAATTGG
TATTTTTTATTGGCACGTTCTGATCCAGATCCTAAAGCTCCTGCTAATAAAGCCTTTACT
GGATTCATTGTGGAAGCAGATACCCCAGGAATTCAGATTGGGAGAAAGGAATTAAACATG
GGCCAGCGATGTTCAGATACTAGAGGAATTGTCTTCGAAGATGTGAAAGTGCCTAAAGAA
AATGTTTTAATTGGTGACGGAGCTGGTTTCAAAGTTGCAATGGGAGCTTTTGATAAAACC
AGACCTGTAGTAGCTGCTGGTGCTGTTGGATTAGCACAAAGAGCTTTGGATGAAGCTACC
AAGTATGCCCTGGAAAGGAAAACTTTCGGAAAGCTACTTGTAGAGCACCAAGCAATATCA
TTTATGCTGGCTGAAATGGCAATGAAAGTTGAACTAGCTAGAATGAGTTACCAGAGAGCA
GCTTGGGAGGTTGATTCTGGTCGTCGAAATACCTATTATGCTTCTATTGCAAAGGCATTT
GCTGGAGATATTGCAAATCAGTTAGCTACTGATGCTGTGCAGATACTTGGAGGCAATGGA
TTTAATACAGAATATCCTGTAGAAAAACTAATGAGGGATGCCAAAATCTATCAGATTTAT
GAAGGTACTTCACAAATTCAAAGACTTATTGTAGCCCGTGAACACATTGACAAGTACAAA
AATTAA
Protein Properties
Number of Residues 421
Molecular Weight 46587.98
Theoretical pI 8.363
Pfam Domain Function
Signals Not Available
Transmembrane Regions Not Available
Protein Sequence 
>Medium-chain specific acyl-CoA dehydrogenase, mitochondrial
MAAGFGRCCRVLRSISRFHWRSQHTKANRQREPGLGFSFEFTEQQKEFQATARKFAREEI
IPVAAEYDKTGEYPVPLIRRAWELGLMNTHIPENCGGLGLGTFDACLISEELAYGCTGVQ
TAIEGNSLGQMPIIIAGNDQQKKKYLGRMTEEPLMCAYCVTEPGAGSDVAGIKTKAEKKG
DEYIINGQKMWITNGGKANWYFLLARSDPDPKAPANKAFTGFIVEADTPGIQIGRKELNM
GQRCSDTRGIVFEDVKVPKENVLIGDGAGFKVAMGAFDKTRPVVAAGAVGLAQRALDEAT
KYALERKTFGKLLVEHQAISFMLAEMAMKVELARMSYQRAAWEVDSGRRNTYYASIAKAF
AGDIANQLATDAVQILGGNGFNTEYPVEKLMRDAKIYQIYEGTSQIQRLIVAREHIDKYK
N
GenBank ID Protein 177964
UniProtKB/Swiss-Prot ID P11310
UniProtKB/Swiss-Prot Entry Name ACADM_HUMAN
PDB IDs
GenBank Gene ID M16827
GeneCard ID ACADM
GenAtlas ID ACADM
HGNC ID HGNC:89
References
General References Not Available