Cannabis Compound Database: Showing Protein Carbonyl reductase [NADPH] 3 (CDBP00074)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP00074

Secondary Accession Numbers

Not Available

Name

Carbonyl reductase [NADPH] 3

Description

Not Available

Synonyms

NADPH-dependent carbonyl reductase 3

Gene Name

CBR3

Protein Type

Enzyme

Biological Properties

General Function

Involved in oxidoreductase activity

Specific Function

Has low NADPH-dependent oxidoreductase activity towards 4-benzoylpyridine and menadione (in vitro).

GO Classification

Biological Process
phylloquinone catabolic process
Cellular Component
cytosol
nucleus
Function
binding
catalytic activity
oxidoreductase activity
Molecular Function
carbonyl reductase (NADPH) activity
3-keto sterol reductase activity
NADPH binding
Process
metabolic process
oxidation reduction

Cellular Location

Cytoplasm

Pathways

Name	SMPDB/Pathwhiz	KEGG
Metabolism of xenobiotics by cytochrome P450	Not Available
Doxorubicin Metabolism Pathway		Not Available

Gene Properties

Chromosome Location

Locus

21q22.2

SNPs

CBR3

Gene Sequence

>834 bp
ATGTCGTCCGGCATCCATGTAGCGCTGGTGACTGGAGGCAACAAGGGCATCGGCTTGGCC
ATCGTGCGCGACCTGTGCCGGCTGTTCTCGGGGGACGTGGTGCTCACGGCGCGGGACGTG
ACGCGGGGCCAGGCGGCCGTACAGCAGCTGCAGGCGGAGGGCCTGAGCCCGCGCTTCCAC
CAGCTGGACATCGACGATCTGCAGAGCATCCGCGCCCTGCGCGACTTCCTGCGCAAGGAG
TACGGGGGCCTGGACGTGCTGGTCAACAACGCGGGCATCGCCTTCAAGGTTGCTGATCCC
ACACCCTTTCATATTCAAGCTGAAGTGACGATGAAAACAAATTTCTTTGGTACCCGAGAT
GTGTGCACAGAATTACTCCCTCTAATAAAACCCCAAGGGAGAGTGGTGAACGTATCTAGC
ATCATGAGCGTCAGAGCCCTTAAAAGCTGCAGCCCAGAGCTGCAGCAGAAGTTCCGCAGT
GAGACCATCACTGAGGAGGAGCTGGTGGGGCTCATGAACAAGTTTGTGGAGGATACAAAG
AAGGGAGTGCACCAGAAGGAGGGCTGGCCCAGCAGCGCATACGGGGTGACGAAGATTGGC
GTCACCGTTCTGTCCAGGATCCACGCCAGGAAACTGAGTGAGCAGAGGAAAGGGGACAAG
ATCCTCCTGAATGCCTGCTGCCCAGGGTGGGTGAGAACTGACATGGCGGGACCCAAGGCC
ACCAAGAGCCCAGAAGAAGGTGCAGAGACCCCTGTGTACTTGGCCCTTTTGCCCCCAGAT
GCTGAGGGTCCCCATGGACAATTTGTTTCAGAGAAGAGAGTTGAACAGTGGTGA

Protein Properties

Number of Residues

277

Molecular Weight

30849.97

Theoretical pI

6.172

Pfam Domain Function

adh_short (PF00106 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Carbonyl reductase [NADPH] 3
MSSCSRVALVTGANRGIGLAIARELCRQFSGDVVLTARDVARGQAAVQQLQAEGLSPRFH
QLDIDDLQSIRALRDFLRKEYGGLNVLVNNAAVAFKSDDPMPFDIKAEMTLKTNFFATRN
MCNELLPIMKPHGRVVNISSLQCLRAFENCSEDLQERFHSETLTEGDLVDLMKKFVEDTK
NEVHEREGWPNSPYGVSKLGVTVLSRILARRLDEKRKADRILVNACCPGPVKTDMDGKDS
IRTVEEGAETPVYLALLPPDATEPQGQLVHDKVVQNW

External Links

GenBank ID Protein

3702679

UniProtKB/Swiss-Prot ID

O75828

UniProtKB/Swiss-Prot Entry Name

CBR3_HUMAN

PDB IDs