Cannabis Compound Database: Showing Protein Deoxycytidylate deaminase (CDBP00002)

Identification Biological properties Gene properties Protein properties External links References XML Show 3 compounds

Identification

HMDB Protein ID

CDBP00002

Secondary Accession Numbers

Not Available

Name

Deoxycytidylate deaminase

Description

Not Available

Synonyms

dCMP deaminase

Gene Name

DCTD

Protein Type

Enzyme

Biological Properties

General Function

Involved in zinc ion binding

Specific Function

Supplies the nucleotide substrate for thymidylate synthetase.

GO Classification

Biological Process
pyrimidine nucleoside biosynthetic process
pyrimidine nucleobase metabolic process
pyrimidine nucleotide metabolic process
nucleotide biosynthetic process
Cellular Component
cytosol
Function
ion binding
cation binding
metal ion binding
binding
catalytic activity
hydrolase activity
hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds
transition metal ion binding
zinc ion binding
Molecular Function
dCMP deaminase activity
metal ion binding
zinc ion binding

Cellular Location

Cytoplasmic

Pathways

Name	SMPDB/Pathwhiz	KEGG
Pyrimidine Metabolism
Beta Ureidopropionase Deficiency		Not Available
UMP Synthase Deficiency (Orotic Aciduria)		Not Available
Dihydropyrimidinase Deficiency		Not Available
MNGIE (Mitochondrial Neurogastrointestinal Encephalopathy)		Not Available

Gene Properties

Chromosome Location

Locus

4q35.1

SNPs

DCTD

Gene Sequence

>537 bp
ATGAGTGAAGTTTCCTGCAAGAAACGGGACGACTATTTGGAATGGCCAGAGTATTTTATG
GCTGTGGCCTTCTTATCAGCACAGAGAAGCAAAGATCCAAATTCCCAGGTCGGCGCCTGC
ATCGTGAATTCAGAAAACAAGATTGTCGGGATTGGGTACAATGGGATGCCAAATGGGTGC
AGTGATGACGTGTTGCCTTGGAGAAGGACAGCAGAGAATAAGCTGGACACCAAATACCCG
TACGTGTGCCATGCGGAGCTGAATGCCATCATGAACAAAAATTCGACCGATGTGAAAGGC
TGTAGTATGTATGTTGCCTTGTTCCCTTGTAATGAATGCGCTAAGCTCATCATCCAGGCA
GGTATAAAAGAAGTGATTTTCATGTCTGATAAATACCATGATAGTGACGAGGCAACTGCT
GCGAGGCTCCTGTTTAATATGGCCGGGGTGACATTCCGGAAATTCATACCGAAGTGCAGC
AAGATTGTCATTGACTTTGATTCAATTAACAGCAGACCGAGTCAAAAGCTTCAGTGA

Protein Properties

Number of Residues

178

Molecular Weight

21013.96

Theoretical pI

7.526

Pfam Domain Function

dCMP_cyt_deam_1 (PF00383 )

Signals

Not Available

Transmembrane Regions

Not Available

Protein Sequence

>Deoxycytidylate deaminase
MSEVSCKKRDDYLEWPEYFMAVAFLSAQRSKDPNSQVGACIVNSENKIVGIGYNGMPNGC
SDDVLPWRRTAENKLDTKYPYVCHAELNAIMNKNSTDVKGCSMYVALFPCNECAKLIIQA
GIKEVIFMSDKYHDSDEATAARLLFNMAGVTFRKFIPKCSKIVIDFDSINSRPSQKLQ

External Links

GenBank ID Protein

61742819

UniProtKB/Swiss-Prot ID

P32321

UniProtKB/Swiss-Prot Entry Name

DCTD_HUMAN

PDB IDs