Record Information |
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Version | 1.0 |
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Created at | 2020-04-27 16:52:35 UTC |
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Updated at | 2021-01-04 18:49:14 UTC |
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CannabisDB ID | CDB005756 |
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Secondary Accession Numbers | Not Available |
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Cannabis Compound Identification |
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Common Name | Phenylbenzimidazole |
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Description | 2-Phenylbenzimidazole also known as Phenizidole or PBZ or PBI is a benzyl derivative of benzimidazole. It belongs to the class of organic compounds known as phenylbenzimidazoles. Phenylbenzimidazoles are compounds containing a phenylbenzimidazole skeleton, which consists of a benzimidazole moiety where its imidazole ring is attached to a phenyl group. 2-Phenylbenzimidazole is one of several structural isomers of phenylbenzimidazole wherein the benzyl group is substituted at different positions of benzimidazole. 2-Phenylbenzimidazole or PBI and 2-phenylbenzimidazole-5-sulfonic acid (PBSA) are ingredients found in some sunscreen agents. PBI can absorb the UV portion of the solar light and undergo a series of light-induced reactions to cause adverse effects in humans (PMID: 17617675 ). Phenylbenzimidazoles are found in cannabis smoke. 2-Phenylbenzimidazole is formed during the combustion of cannabis ( Ref:DOI ). |
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Structure | |
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Synonyms | Value | Source |
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2-Phenyl-1H-benzo(D)imidazole | MeSH | 2-Phenylbenzimidazole | MeSH |
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Chemical Formula | C13H10N2 |
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Average Molecular Weight | 194.24 |
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Monoisotopic Molecular Weight | 194.0844 |
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IUPAC Name | 2-phenyl-1H-1,3-benzodiazole |
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Traditional Name | 2-phenylbenzimidazole |
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CAS Registry Number | 97542-80-8 |
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SMILES | N1C2=CC=CC=C2N=C1C1=CC=CC=C1 |
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InChI Identifier | InChI=1S/C13H10N2/c1-2-6-10(7-3-1)13-14-11-8-4-5-9-12(11)15-13/h1-9H,(H,14,15) |
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InChI Key | DWYHDSLIWMUSOO-UHFFFAOYSA-N |
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Chemical Taxonomy |
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Description | Belongs to the class of organic compounds known as phenylbenzimidazoles. Phenylbenzimidazoles are compounds containing a phenylbenzimidazole skeleton, which consists of a benzimidazole moiety where its imidazole ring is attached to a phenyl group. |
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Kingdom | Organic compounds |
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Super Class | Organoheterocyclic compounds |
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Class | Benzimidazoles |
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Sub Class | Phenylbenzimidazoles |
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Direct Parent | Phenylbenzimidazoles |
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Alternative Parents | |
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Substituents | - Phenylbenzimidazole
- 2-phenylimidazole
- Benzenoid
- Monocyclic benzene moiety
- Heteroaromatic compound
- Imidazole
- Azole
- Azacycle
- Organic nitrogen compound
- Organopnictogen compound
- Hydrocarbon derivative
- Organonitrogen compound
- Aromatic heteropolycyclic compound
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Molecular Framework | Aromatic heteropolycyclic compounds |
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External Descriptors | Not Available |
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Ontology |
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Not Available | Physical Properties |
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State | Not Available |
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Experimental Properties | Property | Value | Reference |
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Melting Point | Not Available | Not Available | Boiling Point | Not Available | Not Available | Water Solubility | Not Available | Not Available | logP | Not Available | Not Available |
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Predicted Properties | [] |
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Spectra |
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EI-MS/GC-MS | Type | Description | Splash Key | View |
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Predicted GC-MS | Phenylbenzimidazole, 1 TMS, Predicted GC-MS Spectrum - 70eV, Positive | Not Available | Spectrum |
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MS/MS | Type | Description | Splash Key | View |
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Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | splash10-0002-0900000000-ff30938fe0ced4db3aae | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | splash10-0002-0900000000-2bdc21e082dabf43fefb | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | splash10-0gdl-9500000000-3fbd90f6ff36f65d9d78 | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | splash10-0006-0900000000-a2491aa954a739ecdee0 | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | splash10-0006-0900000000-a456abbb3d3920a8476c | 2016-08-03 | View Spectrum | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | splash10-00ou-5900000000-94bf83b784bd53545208 | 2016-08-03 | View Spectrum |
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NMR | Not Available |
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Pathways |
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Pathways | Not Available |
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Protein Targets |
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Enzymes | Not Available |
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Transporters | Not Available |
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Metal Bindings | Not Available |
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Receptors | Not Available |
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Transcriptional Factors | Not Available |
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Concentrations Data |
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External Links |
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HMDB ID | Not Available |
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DrugBank ID | Not Available |
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Phenol Explorer Compound ID | Not Available |
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FoodDB ID | Not Available |
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KNApSAcK ID | Not Available |
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Chemspider ID | Not Available |
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KEGG Compound ID | Not Available |
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BioCyc ID | Not Available |
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BiGG ID | Not Available |
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Wikipedia Link | Ensulizole |
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METLIN ID | Not Available |
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PubChem Compound | 12855 |
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PDB ID | Not Available |
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ChEBI ID | Not Available |
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References |
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General References | - Mosley CN, Wang L, Gilley S, Wang S, Yu H: Light-induced cytotoxicity and genotoxicity of a sunscreen agent, 2-phenylbenzimidazole in Salmonella typhimurium TA 102 and HaCaT keratinocytes. Int J Environ Res Public Health. 2007 Jun;4(2):126-31. doi: 10.3390/ijerph2007040006. [PubMed:17617675 ]
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