| Record Information |
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| Version | 1.0 |
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| Created at | 2020-03-19 00:46:32 UTC |
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| Updated at | 2020-12-07 19:07:35 UTC |
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| CannabisDB ID | CDB000610 |
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| Secondary Accession Numbers | Not Available |
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| Cannabis Compound Identification |
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| Common Name | Furfurylmethylamphetamine |
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| Description | Furfurylmethylamphetamine or Furfenorex, belongs to the class of organic compounds known as amphetamines and derivatives. These are organic compounds containing or derived from 1-phenylpropan-2-amine. It is an anorexic drug used in the treatment of obesity (PMID: 2874966 ). One of its metabolites was methamphetamine and has been withdrawn from the market due to abuse potential (PMID: 12024689 ). It is also a stimulant, which enhances the central nervous system activity by mimicking the action of brain neurotransmitters and, due to the ability to increase awareness and counteract fatigue, is misused by athletes participating in sports that require high levels of physical and mental endurances (DOI: 10.1002/9781118533956). Furfurylmethylamphetamine has also been detected as a volatile component in cannabis plant samples obtained from police seizures (PMID: 26657499 ). |
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| Structure | |
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| Synonyms | Not Available |
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| Chemical Formula | C15H19NO |
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| Average Molecular Weight | 229.32 |
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| Monoisotopic Molecular Weight | 229.1467 |
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| IUPAC Name | [(furan-2-yl)methyl](methyl)[(2S)-1-phenylpropan-2-yl]amine |
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| Traditional Name | (furan-2-ylmethyl)(methyl)[(2S)-1-phenylpropan-2-yl]amine |
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| CAS Registry Number | 3776-93-0 |
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| SMILES | C[C@@H](CC1=CC=CC=C1)N(C)CC1=CC=CO1 |
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| InChI Identifier | InChI=1S/C15H19NO/c1-13(11-14-7-4-3-5-8-14)16(2)12-15-9-6-10-17-15/h3-10,13H,11-12H2,1-2H3/t13-/m0/s1 |
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| InChI Key | DLGIIZAHQPTVCJ-ZDUSSCGKSA-N |
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| Chemical Taxonomy |
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| Description | Belongs to the class of organic compounds known as amphetamines and derivatives. These are organic compounds containing or derived from 1-phenylpropan-2-amine. |
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| Kingdom | Organic compounds |
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| Super Class | Benzenoids |
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| Class | Benzene and substituted derivatives |
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| Sub Class | Phenethylamines |
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| Direct Parent | Amphetamines and derivatives |
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| Alternative Parents | |
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| Substituents | - Amphetamine or derivatives
- Phenylpropane
- Aralkylamine
- Furan
- Heteroaromatic compound
- Tertiary amine
- Tertiary aliphatic amine
- Organoheterocyclic compound
- Oxacycle
- Organic nitrogen compound
- Amine
- Hydrocarbon derivative
- Organooxygen compound
- Organonitrogen compound
- Organic oxygen compound
- Aromatic heteromonocyclic compound
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| Molecular Framework | Aromatic heteromonocyclic compounds |
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| External Descriptors | Not Available |
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| Ontology |
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| Role | Industrial application: |
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| Physical Properties |
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| State | Solid |
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| Experimental Properties | | Property | Value | Reference |
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| Melting Point | Not Available | Not Available | | Boiling Point | Not Available | Not Available | | Water Solubility | Not Available | Not Available | | logP | Not Available | Not Available |
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| Predicted Properties | [] |
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| Spectra |
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| EI-MS/GC-MS | Not Available |
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| MS/MS | | Type | Description | Splash Key | View |
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| Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Positive | Not Available | 2020-06-30 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Positive | Not Available | 2020-06-30 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Positive | Not Available | 2020-06-30 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 10V, Negative | Not Available | 2020-06-30 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 20V, Negative | Not Available | 2020-06-30 | View Spectrum | | Predicted MS/MS | Predicted LC-MS/MS Spectrum - 40V, Negative | Not Available | 2020-06-30 | View Spectrum |
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| NMR | Not Available |
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| Pathways |
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| Pathways | Not Available |
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| Protein Targets |
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| Enzymes | Not Available |
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| Transporters | Not Available |
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| Metal Bindings | Not Available |
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| Receptors | Not Available |
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| Transcriptional Factors | Not Available |
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| Concentrations Data |
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| Not Available |
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| External Links |
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| HMDB ID | Not Available |
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| DrugBank ID | Not Available |
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| Phenol Explorer Compound ID | Not Available |
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| FoodDB ID | Not Available |
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| KNApSAcK ID | Not Available |
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| Chemspider ID | 31046444 |
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| KEGG Compound ID | Not Available |
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| BioCyc ID | Not Available |
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| BiGG ID | Not Available |
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| Wikipedia Link | Not Available |
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| METLIN ID | Not Available |
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| PubChem Compound | 71777433 |
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| PDB ID | Not Available |
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| ChEBI ID | Not Available |
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| References |
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| General References | - Harris LS: The stimulants and hallucinogens under consideration: a brief overview of their chemistry and pharmacology. Drug Alcohol Depend. 1986 Jun;17(2-3):107-18. doi: 10.1016/0376-8716(86)90002-5. [PubMed:2874966 ]
- Cody JT: Precursor medications as a source of methamphetamine and/or amphetamine positive drug testing results. J Occup Environ Med. 2002 May;44(5):435-50. doi: 10.1097/00043764-200205000-00012. [PubMed:12024689 ]
- Rice S, Koziel JA: Characterizing the Smell of Marijuana by Odor Impact of Volatile Compounds: An Application of Simultaneous Chemical and Sensory Analysis. PLoS One. 2015 Dec 10;10(12):e0144160. doi: 10.1371/journal.pone.0144160. eCollection 2015. [PubMed:26657499 ]
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